Evaluating the promise of inclusion of African ancestry populations in genomics

AR Bentley, SL Callier, CN Rotimi - NPJ genomic medicine, 2020 - nature.com
The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …

Implications of asymptomatic infection for the natural history of selected parasitic tropical diseases

J Alvar, F Alves, B Bucheton, L Burrows… - Seminars in …, 2020 - Springer
Progress has been made in the control or elimination of tropical diseases, with a significant
reduction of incidence. However, there is a risk of re-emergence if the factors fueling …

Genome-wide association study of trypanosome prevalence and morphometric traits in purebred and crossbred Baoulé cattle of Burkina Faso

B Yougbaré, A Soudré, D Ouédraogo, BL Zoma… - PloS one, 2021 - journals.plos.org
In this study, single-SNP GWAS analyses were conducted to find regions affecting tolerance
against trypanosomosis and morphometrics traits in purebred and crossbred Baoulé cattle of …

The role of HLA‐G in parasitic diseases

A Sabbagh, P Sonon, I Sadissou, CT Mendes‐Junior… - Hla, 2018 - Wiley Online Library
Little attention has been devoted to the role of HLA‐G gene and molecule on parasitic
disorders, and the available studies have focused on malaria, African and American …

Immunomodulatory Potential of Non-Classical HLA-G in Infections including COVID-19 and Parasitic Diseases

S Rashidi, C Vieira, R Tuteja, R Mansouri… - Biomolecules, 2022 - mdpi.com
Human Leukocyte Antigen-G (HLA-G), a polymorphic non-classical HLA (HLA-Ib) with
immune-regulatory properties in cancers and infectious diseases, presents both membrane …

[PDF][PDF] The H3Africa Consortium: publication outputs of a pan-African genomics collaboration (2013 to 2020)

A Choudhury, D Sengupta, S Aron… - Africa, the Cradle of …, 2021 - library.oapen.org
Developing a complex collaborative program across multiple African countries,
characterized by a diversity of government models, laws, cultures and norms, resources and …

No evidence for association between APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations

MP Kimuda, H Noyes, J Mulindwa… - PLoS neglected …, 2018 - journals.plos.org
Background Human African trypanosomiasis (HAT) manifests as an acute form caused by
Trypanosoma brucei rhodesiense (Tbr) and a chronic form caused by Trypanosoma brucei …

The complex health seeking pathway of a human African trypanosomiasis patient in Côte d'Ivoire underlines the need of setting up passive surveillance systems

M Koné, EK N'Gouan, D Kaba, M Koffi… - PLoS Neglected …, 2020 - journals.plos.org
Background Significant efforts to control human African trypanosomiasis (HAT) over the two
past decades have resulted in drastic decrease of its prevalence in Côte d'Ivoire. In this …

Sleeping sickness in the 'Omics era

N Tiberti, JC Sanchez - PROTEOMICS–Clinical Applications, 2018 - Wiley Online Library
Sleeping sickness is a neglected tropical disease caused by Trypanosoma brucei parasites,
affecting the poorest communities in sub‐Saharan Africa. The great efforts done by the …

Association between IL1 gene polymorphism and human African trypanosomiasis in populations of sleeping sickness foci of southern Cameroon

E Ofon, H Noyes, V Ebo'o Eyanga… - PLoS Neglected …, 2019 - journals.plos.org
Background Human African Trypanosomiasis (HAT) is a neglected tropical disease caused
by infections due to Trypanosoma brucei subspecies. In addition to the well-established …