Exosomes are nano-sized membrane extracellular vesicles which can be released from
various types of cells. Exosomes originating from inflammatory or injured cells can have …

Ferroptosis represents a novel non-apoptotic form of regulated cell death that is driven by
iron-dependent lipid peroxidation and plays vital roles in various diseases including …

Acetaminophen (APAP) overdose has long been considered a major cause of drug-induced
liver injury. Ferroptosis is a type of programmed cell death mediated by iron-dependent lipid …

Background Exosomes from adipose-derived stem cells (ADSCs-Exos) have exhibited a
therapeutic role in diabetic nephropathy (DN). Further studies are needed to investigate how …

Aims Neuroinflammation in the spinal dorsal horn (SDH) region plays an important role in
the pathogenesis of interstitial cystitis (IC)/bladder pain syndrome (BPS). Oxidative stress is …

Background Wilson's disease (WD), an autosomal recessive genetic disease, is
characterized by copper metabolism disorder. WD patients may have a series of cognitive …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive loss
of neurons in the brain. However, there are no effective drugs for AD. Mesenchymal stem …

Iron homeostasis is crucial for maintaining proper cellular function, and its disruption is
considered one of the pathogenic mechanisms underlying musculoskeletal diseases. Under …

Vascular dementia (VD) is a prevalent cognitive disorder among the elderly. Its pathological
mechanism encompasses neuronal damage, synaptic dysfunction, vascular abnormalities …

Mesenchymal stem cells-derived exosomes (MSC-Exo) are considered to have great
potential in the treatment of human diseases. However, the role of MSC-Exo in the process …