Nrf2 regulates oxidative stress and its role in cerebral ischemic stroke
Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …
[HTML][HTML] Flavonoids against the SARS-CoV-2 induced inflammatory storm
The disease severity of COVID-19, especially in the elderly and patients with co-morbidities,
is characterized by hypercytokinemia, an exaggerated immune response associated with an …
is characterized by hypercytokinemia, an exaggerated immune response associated with an …
Natural products as modulators of Nrf2 signaling pathway in neuroprotection
I Moratilla-Rivera, M Sánchez… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases (NDs) affect the West due to the increase in life expectancy.
Nervous cells accumulate oxidative damage, which is one of the factors that triggers and …
Nervous cells accumulate oxidative damage, which is one of the factors that triggers and …
Flavonoids and mitochondria: activation of cytoprotective pathways?
A Kicinska, W Jarmuszkiewicz - Molecules, 2020 - mdpi.com
A large number of diverse mechanisms that lead to cytoprotection have been described to
date. Perhaps, not surprisingly, the role of mitochondria in these phenomena is notable. In …
date. Perhaps, not surprisingly, the role of mitochondria in these phenomena is notable. In …
Flavonoid-rich extracts from okra flowers exert antitumor activity in colorectal cancer through induction of mitochondrial dysfunction-associated apoptosis, senescence …
Y Deng, S Li, M Wang, X Chen, L Tian, L Wang… - Food & function, 2020 - pubs.rsc.org
Okra flowers contain a higher content of total flavonoids than most other flowers; however
little research has been conducted on their potential benefits, including antitumor activity. In …
little research has been conducted on their potential benefits, including antitumor activity. In …
Effects of compound K, a metabolite of ginsenosides, on memory and cognitive dysfunction in db/db mice involve the inhibition of ER stress and the NLRP3 …
CW Li, MZ Deng, ZJ Gao, YY Dang, GD Zheng… - Food & function, 2020 - pubs.rsc.org
Accumulating clinical and epidemiological evidence indicates a close relationship between
diabetes mellitus and dementia. The ginsenoside compound K (CK) has been reported to …
diabetes mellitus and dementia. The ginsenoside compound K (CK) has been reported to …
Targeting Nrf2 signaling pathway by quercetin in the prevention and treatment of neurological disorders: An overview and update on new developments
MY Zamanian, A Soltani, Z Khodarahmi… - Fundamental & …, 2023 - Wiley Online Library
Abstract Background: Neurological disorders (NLDs) are widely acknowledged as a
significant public health concern worldwide. Stroke, Alzheimer's disease (AD), and traumatic …
significant public health concern worldwide. Stroke, Alzheimer's disease (AD), and traumatic …
Protective effects and mechanisms of action of ulinastatin against cerebral ischemia-reperfusion injury
B Lv, XM Jiang, DW Wang, J Chen… - Current …, 2020 - ingentaconnect.com
Background: Cerebral ischemia-reperfusion injury is an extremely complicated pathological
process that is clinically characterized by high rates of disability and mortality. It is imperative …
process that is clinically characterized by high rates of disability and mortality. It is imperative …
A review of the protective effects of quercetin-rich natural compounds for treating ischemia-reperfusion injury
SS Javadinia, K Abbaszadeh-Goudarzi… - Biotechnic & …, 2022 - Taylor & Francis
Ischemia-reperfusion (IR) injury causes dysfunction of tissues and organs, and oxidative
stress plays an important role. During IR, reactive oxygen species (ROS) are increased …
stress plays an important role. During IR, reactive oxygen species (ROS) are increased …
Prunus cerasoides Extract and Its Component Compounds Upregulate Neuronal Neuroglobin Levels, Mediate Antioxidant Effects, and Ameliorate Functional Losses …
SD Kim, M Kim, HH Wu, BK Jin, MS Jeon, YS Song - Antioxidants, 2021 - mdpi.com
Prunus cerasoides (PC) has been reported to have antimicrobial and anti-inflammatory
properties, but its potential as a neuroprotective agent in a mouse model of cerebral …
properties, but its potential as a neuroprotective agent in a mouse model of cerebral …