The advent of single-cell biology opens a new chapter for understanding human biological
processes and for diagnosing, monitoring, and treating disease. This revolution now …

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipid-
rich plaques within arterial walls. T cells play a pivotal role in the pathogenesis of …

Atherosclerotic cardiovascular disease is a major cause of disability and death worldwide.
Most therapeutic approaches target traditional risk factors but ignore the fundamental role of …

The mechanisms of cardiovascular diseases (CVDs) remain incompletely elucidated. Single-
cell RNA sequencing (scRNA-seq) has enabled the profiling of single-cell transcriptomes at …

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and
mortality worldwide. Even with excellent control of low-density lipoprotein cholesterol (LDL …

Incidence and mortality rates for cardiovascular disease are declining, but it still remains a
major cause of morbidity and mortality. Drug treatments to slow the progression of …

The development and rupture of atherosclerotic plaques is a major contributor to myocardial
infarctions and ischemic strokes. The dynamic evolution of the plaque is largely attributed to …

Mounting experimental and clinical evidence has revealed that adaptive immune
mechanisms targeting myocardial antigens are triggered by different forms of cardiac injury …

Patients with chronic kidney disease (CKD) suffer from marked cardiovascular morbidity and
mortality, so lowering the cardiovascular risk is paramount to improve quality of life and …

The immune system plays a vital role in maintaining tissue integrity and organismal
homeostasis. The sudden stress caused by myocardial infarction (MI) poses a significant …