The field of Cannabis sativa L. research for medical purposes has been rapidly advancing in
recent decades and a growing body of evidence suggests that phytocannabinoids are …

Medical cannabis use is increasing worldwide. Clinicians are commonly asked by patients
to provide guidance on its safety and efficacy. Although there has been an increase in …

The most frequently reported use of medical marijuana is for pain relief. However, its
psychoactive component Δ9-tetrahydrocannabinol (THC) causes significant side effects …

Introduction Pharmacotherapeutic options continue to expand for the treatment of chronic
non-cancer pain. There has been an increasing emphasis on multimodal analgesia. This …

Background: Chronic non-cancer pain (CNCP) is estimated to affect 20% of the adult
population. Current United States and Canadian Chronic non-cancer pain guidelines …

Importance Patients with chronic pain often receive long-term opioid therapy (LOT), which
places them at risk of opioid use disorder and overdose. This presents the need for …

Aging is a complex phenomenon associated with a wide spectrum of physical and
physiological changes affecting every part of all metazoans, if they escape death prior to …

Clinicians play an important role in promoting safe and responsible medical cannabis use.
One essential component to safe use is considering a patient's risk of neurocognitive …

Background There is a growing literature on the potential medical uses of Cannabis sativa
and cannabinoid compounds. Although these have only been approved by regulatory …

Cannabidiol (CBD), the major non-intoxicating constituent of Cannabis sativa, has gained
recent attention due to its putative therapeutic uses for a wide variety of diseases. CBD was …