Pertussis is a severe respiratory infection caused by Bordetella pertussis, and in 2008,
pertussis was associated with an estimated 16 million cases and 195,000 deaths globally …

Importance Parents hesitant to vaccinate their children may delay routine immunizations or
seek exemptions from state vaccine mandates. Recent outbreaks of vaccine-preventable …

Pertussis is an acute respiratory disease caused by Bordetella pertussis. Due to its
frequency and severity, prevention of pertussis has been considered an important public …

Protective immunity wanes rapidly after immunization of children with acellular pertussis
(aP) vaccines and these vaccines do not prevent nasal colonization or transmission of …

The resurgence of pertussis over the past decades has resulted in incidence levels not
witnessed in the United States since the 1950s. The underlying causes have been the …

Pertussis is resurgent in some countries, particularly those in which children receive
acellular pertussis (aP) vaccines in early infancy and boosters later in life. Immunologic …

Highlights-Vaccination against pertussis in pregnancy is safe for pregnant women and
newborns.-Vaccination against pertussis during the second or early third trimester of …

Pertussis is a highly contagious acute respiratory illness classically known as “whooping
cough” because of its characteristic cough. The majority of cases are caused by Bordetella …

Background: A resurgence of pertussis cases among both vaccinated and unvaccinated
people raises questions about vaccine effectiveness over time. Our objective was to study …

Outer Membrane Vesicles (OMVs) derived from different Gram-negative bacteria have been
proposed as an attractive vaccine platform because of their own immunogenic adjuvant …