Tubulin-interactive natural products as anticancer agents
DGI Kingston - Journal of natural products, 2009 - ACS Publications
This review provides an overview of the discovery, structures, and biological activities of
anticancer natural products that act by inhibiting or promoting the assembly of tubulin to …
anticancer natural products that act by inhibiting or promoting the assembly of tubulin to …
Potential of plant-derived natural products in the treatment of leukemia and lymphoma
DM Lucas, PC Still, L Bueno Perez… - Current drug …, 2010 - ingentaconnect.com
Hematologic malignancies account for a substantial percentage of cancers worldwide, and
the heterogeneity and biological characteristics of leukemias and lymphomas present …
the heterogeneity and biological characteristics of leukemias and lymphomas present …
Natural bioactive lead compounds effective against haematological malignancies
The treatment of hematological diseases has evolved tremendously during the past
decades. The discovery of new drugs has permitted us to target even the most subtle …
decades. The discovery of new drugs has permitted us to target even the most subtle …
Electrochemical evaluation and determination of vindesine used in cancer chemotherapy at disposable pencil graphite electrode by voltammetric method
Here, the electrochemical properties and detection of vindesine on the working electrode
surface of disposable pencil graphite electrode were determined by cyclic voltammetry and …
surface of disposable pencil graphite electrode were determined by cyclic voltammetry and …
[HTML][HTML] Cell death signaling and anticancer therapy
L Galluzzi, I Vitale, E Vacchelli, G Kroemer - Frontiers in oncology, 2011 - frontiersin.org
For a long time, it was commonly believed that efficient anticancer regimens would either
trigger the apoptotic demise of tumor cells or induce a permanent arrest in the G1 phase of …
trigger the apoptotic demise of tumor cells or induce a permanent arrest in the G1 phase of …
Natural products as pharmaceuticals and sources for lead structures
DJ Newman, GM Cragg, DGI Kingston - The practice of medicinal …, 2008 - Elsevier
Publisher Summary Plant-based systems continue to play an essential role in health care,
and their use by different cultures is extensively documented. This chapter reviews the …
and their use by different cultures is extensively documented. This chapter reviews the …
Inadvertent intrathecal injections and best practice management
The intrathecal space has become an important anatomic site for medical intervention not
only in anesthesia practice, but also in many other medical specialties …
only in anesthesia practice, but also in many other medical specialties …
Plant secondary metabolites in cancer chemotherapy: where are we?
DM Pereira, P Valentao… - Current …, 2012 - ingentaconnect.com
Nowadays we have a number of chemical and biological agents at our disposal to treat
chronic pathologies such as cancer. Although most drugs display significant activity, thus …
chronic pathologies such as cancer. Although most drugs display significant activity, thus …
Anticancer prodrugs: An overview of major strategies and recent developments
Research in anticancer chemotherapy has produced outstanding results, and mean survival
rates have significantly improved over the last ten years. Nevertheless, all approved drugs …
rates have significantly improved over the last ten years. Nevertheless, all approved drugs …
Synthesis and fungicidal activity of quinolin-6-yloxyacetamides, a novel class of tubulin polymerization inhibitors
C Lamberth, FM Kessabi, R Beaudegnies… - Bioorganic & Medicinal …, 2014 - Elsevier
A novel class of experimental fungicides has been discovered, which consists of special
quinolin-6-yloxyacetamides. They are highly active against important phytopathogens, such …
quinolin-6-yloxyacetamides. They are highly active against important phytopathogens, such …