Pathobiology of cognitive impairment in Parkinson disease: challenges and outlooks

KA Jellinger - International Journal of Molecular Sciences, 2023 - mdpi.com
Cognitive impairment (CI) is a characteristic non-motor feature of Parkinson disease (PD)
that poses a severe burden on the patients and caregivers, yet relatively little is known about …

Mild cognitive impairment in Parkinson's disease: current view

KA Jellinger - Frontiers in Cognition, 2024 - frontiersin.org
Parkinson's disease (PD), the most common motor movement disorder and second most
common neurodegenerative disorder after Alzheimer's disease (AD), is often preceded by a …

[HTML][HTML] Intelligent cholinergic white matter pathways algorithm based on U-net reflects cognitive impairment in patients with silent cerebrovascular disease

B Fei, Y Cheng, Y Liu, G Zhang, A Ge, J Luo… - Stroke and Vascular …, 2024 - svn.bmj.com
Background and objective The injury of the cholinergic white matter pathway underlies
cognition decline in patients with silent cerebrovascular disease (SCD) with white matter …

Cholinergic hyperintensity pathways are associated with cognitive performance in patients with asymptomatic carotid artery stenosis

S Xu, S Yu, B Mao, J Yang, S Wan, F Fu - Clinical Neurology and …, 2024 - Elsevier
Objectives We aimed to determine whether asymptomatic carotid artery stenosis (ACS)
induced cognitive impairments were related to the cholinergic hyperintensity pathway …

Structural network topology mediated cognitive impairment in Parkinson's disease

Z Chen, G Li, L Zhou, L Zhang, L Yang, J Liu - medRxiv, 2023 - medrxiv.org
Cognitive impairment (CI) is one of the most prominent non-motor symptoms in Parkinson's
disease (PD). How brain network abnormalities contribute to CI in PD patients remain …

Lateral Thinking: Pathway Specific Neurodegeneration of the Cortical Cholinergic System in Alzheimer's Disease

RA Crockett, C Casselton, TM Howard, KB Wilkins… - medRxiv, 2024 - medrxiv.org
INTRODUCTION: Atrophy of the nucleus basalis of Meynert (NBM) is an early indicator of
Alzheimer's disease (AD). However, reduced integrity of the NBM white matter tracts may be …