Fibrosis, defined by the excess deposition of structural and matricellular proteins in the
extracellular space, underlies tissue dysfunction in multiple chronic diseases. Approved …

Type 2 diabetes mellitus (T2DM) is characterized by tissue-specific insulin resistance and
pancreatic β-cell dysfunction, which result from the interplay of local abnormalities within …

Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver
disease worldwide. Although NAFLD is tightly linked to obesity and type 2 diabetes, this liver …

The objective of this review is to provide a comprehensive summary of the latest
methodological advancements and emerging patterns in utilizing lipidomics in clinical …

Differential sensing attempts to mimic the mammalian senses of smell and taste to identify
analytes and complex mixtures. In place of hundreds of complex, membrane-bound G …

Ceramides are signals of fatty acid excess that accumulate when a cell's energetic needs
have been met and its nutrient storage has reached capacity. As these sphingolipids accrue …

Non-alcoholic fatty liver disease (NAFLD) pathogenesis remains poorly understood due to
the complex metabolic and inflammatory changes in the liver. This study aimed to elucidate …

Portal hypertension (PH) has traditionally been observed as a consequence of significant
fibrosis and cirrhosis in advanced non-alcoholic fatty liver disease (NAFLD). However …

Metabolic-associated fatty liver disease (MAFLD) refers to the build-up of fat in the liver
associated with metabolic dysfunction and has been estimated to affect a quarter of the …

Metabolomics as a tool to predict the risk of decompensation... : Hepatology Metabolomics as a
tool to predict the risk of decompensation or liver-related death in patients with compensated …