Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression
Atrial fibrillation (AF) is the most common clinically relevant arrhythmia and is associated
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
with increased morbidity and mortality. The incidence of AF is expected to continue to rise …
Atrial fibrillation from the pathologist's perspective
D Corradi - Cardiovascular pathology, 2014 - Elsevier
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia encountered in clinical
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …
Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation
Aims Genetic factors may be important in the development of atrial fibrillation (AF) in the
young. KCNA5 encodes the potassium channel α-subunit KV1. 5, which underlies the …
young. KCNA5 encodes the potassium channel α-subunit KV1. 5, which underlies the …
Pitx2, an Atrial Fibrillation Predisposition Gene, Directly Regulates Ion Transport and Intercalated Disc Genes
Background—Pitx2 is the homeobox gene located in proximity to the human 4q25 familial
atrial fibrillation (AF) locus. When deleted in the mouse germline, Pitx2 haploinsufficiency …
atrial fibrillation (AF) locus. When deleted in the mouse germline, Pitx2 haploinsufficiency …
PITX2‐dependent gene regulation in atrial fibrillation and rhythm control
F Syeda, P Kirchhof, L Fabritz - The Journal of Physiology, 2017 - Wiley Online Library
Atrial fibrillation (AF) is a common arrhythmia. Better prevention and treatment of AF are
needed to reduce AF‐associated morbidity and mortality. There are several major …
needed to reduce AF‐associated morbidity and mortality. There are several major …
[HTML][HTML] Application of single-nucleotide polymorphism-related risk estimates in identification of increased genetic susceptibility to cardiovascular diseases: a literature …
S Fiatal, R Adany - Frontiers in public health, 2018 - frontiersin.org
Background Although largely preventable, cardiovascular diseases (CVDs) are the biggest
cause of death worldwide. Common complex cardiovascular disorders (eg, coronary heart …
cause of death worldwide. Common complex cardiovascular disorders (eg, coronary heart …
Atrial fibrillation risk loci interact to modulate Ca2+-dependent atrial rhythm homeostasis
B Laforest, W Dai, L Tyan, S Lazarevic… - The Journal of …, 2019 - Am Soc Clin Investig
Atrial fibrillation (AF), defined by disorganized atrial cardiac rhythm, is the most prevalent
cardiac arrhythmia worldwide. Recent genetic studies have highlighted a major heritable …
cardiac arrhythmia worldwide. Recent genetic studies have highlighted a major heritable …
Multiple roles of Pitx2 in cardiac development and disease
D Franco, D Sedmera, E Lozano-Velasco - Journal of cardiovascular …, 2017 - mdpi.com
Cardiac development is a complex morphogenetic process initiated as bilateral cardiogenic
mesoderm is specified at both sides of the gastrulating embryo. Soon thereafter, these …
mesoderm is specified at both sides of the gastrulating embryo. Soon thereafter, these …
[HTML][HTML] Electrocardiogram (ECG) for the prediction of incident atrial fibrillation: an overview
Y Aizawa, H Watanabe, K Okumura - Journal of atrial fibrillation, 2017 - ncbi.nlm.nih.gov
Electrocardiograms (ECGs) have been employed to medically evaluate participants in
population-based studies, and ECG-derived predictors have been reported for incident atrial …
population-based studies, and ECG-derived predictors have been reported for incident atrial …
South Asian ethnicity is associated with a lower prevalence of atrial fibrillation despite greater prevalence of established risk factors: a population-based study in …
RG Gillott, K Willan, K Kain, UM Sivananthan… - Ep …, 2017 - academic.oup.com
Aims Previous studies indicate that South Asians (SAs) may have a reduced risk of
developing atrial fibrillation (AF) despite having a higher prevalence of traditional …
developing atrial fibrillation (AF) despite having a higher prevalence of traditional …