Caffeine and melatonin have been shown to protect the Swedish mutant amyloid precursor
protein (APPsw) transgenic mouse model of Alzheimer's disease from cognitive dysfunction …

ATP-sensitive potassium channels (K ATP channels), a group of vital channels that link the
electrical activity of the cell membrane with cell metabolism, were discovered on the …

With more than 80 subunits, potassium (K+) channels represent a group of ion channels
showing high degree of diversity and ubiquity. They play important role in the control of …

Abstract Late Onset Alzheimer's Disease is the most common cause of dementia,
characterized by extracellular deposition of plaques primarily of amyloid-β (Aβ) peptide and …

Mitochondrial metabolism is highly responsive to nutrient availability and ongoing activity in
neuronal circuits. The molecular mechanisms by which brain cells respond to an increase in …

Alzheimer's disease (AD) is characterized by the deposition of amyloid β peptide (Aβ) in the
brain. The neuropeptide somatostatin (SST) regulates Aβ catabolism by enhancing …

Alzheimer's disease (AD) is the major form of dementia prevalent in older adults and with a
high incidence in females. Identification of early biomarkers is essential for preventive …

Dietary and metabolic therapies are increasingly being considered for a variety of
neurological disorders, based in part on growing evidence for the neuroprotective properties …

This review describes neuroprotective effects mediated by pre-and post-conditioning-
induced processes that act via the quantitative features of the hormetic dose response …

Alzheimer's disease (AD) involves the progressive degeneration of neurons critical for
learning and memory. In addition, patients with AD typically exhibit impaired olfaction …