Equine maternal aging affects the metabolomic profile of oocytes and follicular cells during different maturation time points
Introduction: Oocyte quality and fertility decline with advanced maternal age. During
maturation within the ovarian follicle, the oocyte relies on the associated somatic cells …
maturation within the ovarian follicle, the oocyte relies on the associated somatic cells …
Cryopreservation of equine spermatozoa reduces plasma membrane integrity and phospholipase C zeta 1 content as associated with oocyte activation
RA Gonzalez‐Castro, LA Whitcomb, EC Pinsinski… - …, 2024 - Wiley Online Library
Abstract Background Phospholipase C zeta (PLCZ1) is considered the major sperm‐borne
oocyte activation factor. Cryopreserved stallion spermatozoa are commonly used for …
oocyte activation factor. Cryopreserved stallion spermatozoa are commonly used for …
Adiposity in mares induces insulin dysregulation and mitochondrial dysfunction which can be mitigated by nutritional intervention
K Fresa, GD Catandi, L Whitcomb… - Scientific Reports, 2024 - nature.com
Obesity is a complex disease associated with augmented risk of metabolic disorder
development and cellular dysfunction in various species. The goal of the present study was …
development and cellular dysfunction in various species. The goal of the present study was …
Follicular metabolic alterations are associated with obesity in mares and can be mitigated by dietary supplementation
GD Catandi, KJ Fresa, MH Cheng, LA Whitcomb… - Scientific reports, 2024 - nature.com
Obesity is a growing concern in human and equine populations, predisposing to metabolic
pathologies and reproductive disturbances. Cellular lipid accumulation and mitochondrial …
pathologies and reproductive disturbances. Cellular lipid accumulation and mitochondrial …
Effect of pentobarbital as a euthanasia agent on equine in vitro embryo production
S Martin-Pelaez, Z Rabow, A De la Fuente, P Draheim… - Theriogenology, 2023 - Elsevier
Postmortem and pre-euthanasia oocyte retrieval provides the last opportunity to preserve
the genetic material in mares. Pentobarbital (PB) is the most common euthanasia agent; …
the genetic material in mares. Pentobarbital (PB) is the most common euthanasia agent; …
Maturation and culture affect the metabolomic profile of oocytes and follicular cells in young and old mares
DR Bresnahan, GD Catandi, SO Peters… - Frontiers in Cell and …, 2024 - frontiersin.org
Introduction: Oocytes and follicular somatic cells within the ovarian follicle are altered during
maturation and after exposure to culture in vitro. In the present study, we used a nontargeted …
maturation and after exposure to culture in vitro. In the present study, we used a nontargeted …
Preovulatory follicular fluid secretome added to in vitro maturation medium influences the metabolism of equine cumulus-oocyte complexes
M Luis-Calero, JM Ortiz-Rodríguez… - BMC veterinary …, 2024 - Springer
Background In vitro embryo production is a highly demanded reproductive technology in
horses, which requires the recovery (in vivo or post-mortem) and in vitro maturation (IVM) of …
horses, which requires the recovery (in vivo or post-mortem) and in vitro maturation (IVM) of …
[HTML][HTML] Characterization of preovulatory follicular fluid secretome and its effects on equine oocytes during in vitro maturation
M Luis-Calero, F Marinaro… - Research in Veterinary …, 2024 - Elsevier
In vitro maturation (IVM) of oocytes is clinically used in horses to produce blastocysts but
current conditions used for horses are suboptimal. We analyzed the composition of equine …
current conditions used for horses are suboptimal. We analyzed the composition of equine …
L-carnitine enhances developmental potential of bovine oocytes matured under high lipid concentrations in vitro
Maternal obesity elevates non-esterified fatty acids (NEFA) follicular concentrations. Bovine
cumulus-oocyte complexes (COCs) matured in vitro under high NEFA have altered …
cumulus-oocyte complexes (COCs) matured in vitro under high NEFA have altered …
Lipid metabolites, interleukin-6 and oxidative stress markers in follicular fluid and their association with serum concentrations in mares
The application of trans-vaginal ovum pick up (OPU) and intracytoplasmic sperm injection
(ICSI) is well established for commercial in vitro embryo production in horses. These …
(ICSI) is well established for commercial in vitro embryo production in horses. These …