Wilson disease and other neurodegenerations with metal accumulations

P Dusek, T Litwin, A Czlonkowska - Neurologic clinics, 2015 - neurologic.theclinics.com
Trace elements, such as iron, copper, manganese, and calcium, which are essential
constituents necessary for cellular homeostasis, become toxic when present in excess …

[HTML][HTML] Diagnostic and treatment implications of psychosis secondary to treatable metabolic disorders in adults: a systematic review

O Bonnot, HH Klünemann, F Sedel, S Tordjman… - Orphanet journal of rare …, 2014 - Springer
Objective It is important for psychiatrists to be aware of certain inborn errors of metabolism
(IEMs) as these rare disorders can present as psychosis, and because definitive treatments …

[HTML][HTML] A population-based epidemiology of Wilson's disease in South Korea between 2010 and 2016

EJ Choe, JW Choi, M Kang, YK Lee, HH Jeon… - Scientific Reports, 2020 - nature.com
Very few population-based studies have examined the epidemiology of Wilson's disease
(WD). We investigated the epidemiology of WD using the National Health Insurance Service …

Role for biochemical assays and Kayser-Fleischer rings in diagnosis of Wilson's disease

Y Dong, RM Wang, GM Yang, H Yu, WQ Xu… - Clinical …, 2021 - Elsevier
Background & Aims Wilson disease is an autosomal recessive disorder that impairs copper
homeostasis and is caused by homozygous or compound heterozygous mutations in …

[HTML][HTML] Myelin, copper, and the cuprizone model of schizophrenia

NR Herring, C Konradi - Frontiers in bioscience (Scholar edition), 2011 - ncbi.nlm.nih.gov
In recent years increasing evidence is pointing toward white matter abnormalities in
schizophrenia and other psychiatric disorders. The present paper will provide an overview …

[HTML][HTML] Wilson's disease: An Indian perspective

AB Taly, LK Prashanth, S Sinha - Neurology India, 2009 - journals.lww.com
Wilson's disease (WD) is an autosomal recessive disease involving a defect of copper
transport by the hepatic lysosomes. It leads to excess copper deposition in the liver, the …

[HTML][HTML] Quality of life and psychiatric symptoms in Wilson's disease: the relevance of bipolar disorders

MG Carta, G Mura, O Sorbello, G Farina… - Clinical Practice and …, 2012 - ncbi.nlm.nih.gov
Methods: This is a systematic review. The search of the significant articles was carried out in
PubMed using specific key words. Results: Such other neurological diseases, WD is …

[HTML][HTML] Secondary psychosis induced by metabolic disorders

O Bonnot, PM Herrera, S Tordjman… - Frontiers in …, 2015 - frontiersin.org
Metabolic disorders are not well-recognized by psychiatrists as a possible source of
secondary psychoses. Inborn errors of metabolism (IEMs) are not frequent. Although their …

[PDF][PDF] Cannabinoid‐1 receptor antagonism improves glycemic control and increases energy expenditure through sirtuin‐1/mechanistic target of rapamycin complex 2 …

J Liu, G Godlewski, T Jourdan, Z Liu, R Cinar… - …, 2019 - Wiley Online Library
Endocannabinoids promote energy conservation in obesity, whereas cannabinoid‐1
receptor (CB1R) blockade reverses body weight gain and insulin resistance and increases …

Wilson's disease

RF Pfeiffer - Handbook of clinical neurology, 2011 - Elsevier
In the almost 100 years since Wilson's description of the illness that now bears his name,
tremendous advances have been made in our understanding of this disorder. The genetic …