Airborne aerosols and human health: Leapfrogging from mass concentration to oxidative potential

C Molina, R Toro A, CA Manzano, S Canepari… - Atmosphere, 2020 - mdpi.com
The mass concentration of atmospheric particulate matter (PM) has been systematically
used in epidemiological studies as an indicator of exposure to air pollutants, connecting PM …

Proinflammatory effects and oxidative stress within human bronchial epithelial cells exposed to atmospheric particulate matter (PM2. 5 and PM> 2.5) collected from …

BF Cachon, S Firmin, A Verdin, L Ayi-Fanou… - Environmental …, 2014 - Elsevier
After particulate matter (PM) collection in Cotonou (Benin), a complete physicochemical
characterization of PM 2.5 and PM> 2.5 was led. Then, their adverse health effects were …

Analytical Methods for Physicochemical Characterization and Toxicity Assessment of Atmospheric Particulate Matter: A Review

A Agibayeva, M Guney, F Karaca, A Kumisbek, JR Kim… - Sustainability, 2022 - mdpi.com
Particle-bound pollutants are a critical risk factor for human respiratory/cardiovascular
conditions. A comprehensive analysis of the physicochemical characteristics of PM is often …

Assessment of biological responses of EpiAirway 3-D cell constructs versus A549 cells for determining toxicity of ambient air pollution

J Zavala, B O'Brien, K Lichtveld, KG Sexton… - Inhalation …, 2016 - Taylor & Francis
Context: EpiAirwayTM 3-D constructs are human-derived cell cultures of differentiated
airway epithelial cells that may represent a more biologically relevant model of the human …

Characterization of ABC Transporters in EpiAirway™, a Cellular Model of Normal Human Bronchial Epithelium

BM Rotoli, A Barilli, R Visigalli, F Ferrari, C Frati… - International journal of …, 2020 - mdpi.com
The ATP-binding cassette (ABC) transporters P-glycoprotein (MDR1/ABCB1), multidrug
resistance-associated protein 1 (MRP1/ABCC1), and breast cancer resistance protein …

Gene expression profiling and pathway analysis of human bronchial epithelial cells exposed to airborne particulate matter collected from Saudi Arabia

H Sun, M Shamy, T Kluz, AB Muñoz, M Zhong… - Toxicology and applied …, 2012 - Elsevier
Epidemiological studies have established a positive correlation between human mortality
and increased concentration of airborne particulate matters (PM). However, the mechanisms …

Spleen tyrosine kinase inhibition attenuates airway hyperresponsiveness and pollution-induced enhanced airway response in a chronic mouse model of asthma

PC Penton, X Wang, H Amatullah, J Cooper… - Journal of allergy and …, 2013 - Elsevier
BACKGROUND: Asthma is a chronic inflammatory disease characterized by airways
hyperresponsiveness (AHR), reversible airflow obstruction, airway remodeling, and episodic …

Similar polycyclic aromatic hydrocarbon and genotoxicity profiles of atmospheric particulate matter from cities on three different continents

BS Maselli, V Cunha, H Lim, C Bergvall… - Environmental and …, 2020 - Wiley Online Library
The extractable organic material (EOM) from atmospheric total suspended particles (TSP)
contains several organic compounds including non‐substituted polycyclic aromatic …

The Gillings Sampler–An electrostatic air sampler as an alternative method for aerosol in vitro exposure studies

J Zavala, K Lichtveld, S Ebersviller, JL Carson… - Chemico-biological …, 2014 - Elsevier
There is growing interest in studying the toxicity and health risk of exposure to multi-pollutant
mixtures found in ambient air, and the US Environmental Protection Agency (EPA) is moving …

Numerical and experimental study on the deposition of nanoparticles in an extrathoracic oral airway model

F Krause, A Wenk, C Lacor, WG Kreyling… - Journal of Aerosol …, 2013 - Elsevier
We studied the transport and deposition of quasi-monodisperse nanoparticles (with mobility
diameter dm ranging from 1nm to 52nm) inside an extrathoracic airway model (which …