Biosystem‐inspired engineering of nanozymes for biomedical applications
L Zhang, H Wang, X Qu - Advanced Materials, 2024 - Wiley Online Library
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …
become surrogates of natural enzymes in many fields by virtue of their advantages of high …
Bioactive Iridium Nanoclusters with Glutathione Depletion Ability for Enhanced Sonodynamic‐Triggered Ferroptosis‐Like Cancer Cell Death
T Nie, W Zou, Z Meng, L Wang, T Ying, X Cai… - Advanced …, 2022 - Wiley Online Library
Ferroptosis is a regulated form of necrotic cell death that involves the accumulation of lipid
peroxide (LPO) species in an iron‐and reactive oxygen species (ROS)‐dependent manner …
peroxide (LPO) species in an iron‐and reactive oxygen species (ROS)‐dependent manner …
Nanozyme-based strategies for efficient theranostics of brain diseases
R Xu, S Zhang, P Wang, R Zhang, P Lin, Y Wang… - Coordination Chemistry …, 2024 - Elsevier
Oxidative stress emerges as a critical mechanism underlying the development and
progression of various brain diseases, arising from either increased generation of reactive …
progression of various brain diseases, arising from either increased generation of reactive …
[HTML][HTML] Pathological BBB crossing melanin-like nanoparticles as metal-ion chelators and neuroinflammation regulators against Alzheimer's disease
Q Huang, C Jiang, X Xia, Y Wang, C Yan, X Wang… - Research, 2023 - spj.science.org
Inflammatory responses, manifested in excessive oxidative stress and microglia
overactivation, together with metal ion-triggered amyloid-beta (Aβ) deposition, are critical …
overactivation, together with metal ion-triggered amyloid-beta (Aβ) deposition, are critical …
Redox homeostasis strategy for inflammatory macrophage reprogramming in rheumatoid arthritis based on ceria oxide nanozyme-complexed biopolymeric micelles
F Zhou, M Li, M Chen, M Chen, X Chen, Z Luo, K Cai… - ACS …, 2023 - ACS Publications
The synovial tissues under rheumatoid arthritis conditions are usually infiltrated by
inflammatory cells, particularly M1 macrophages with aberrant redox homeostasis, which …
inflammatory cells, particularly M1 macrophages with aberrant redox homeostasis, which …
Clustered cobalt nanodots initiate ferroptosis by upregulating heme oxygenase 1 for radiotherapy sensitization
J Zhao, Y Chen, T Xiong, S Han, C Li, Y He, Y He… - Small, 2023 - Wiley Online Library
High cobalt (Co) levels in tumors are associated with good clinical prognosis. An anticancer
regimen that increases intratumoral Co through targeted nanomaterial delivery is proposed …
regimen that increases intratumoral Co through targeted nanomaterial delivery is proposed …
Post-remedial oxygen supply: a new perspective on photodynamic therapy to suppress tumor metastasis
Photodynamic therapy (PDT) holds great promise in tumor therapy due to high safety,
efficacy, and specificity. However, the risk of increased metastasis in hypoxic tumors after …
efficacy, and specificity. However, the risk of increased metastasis in hypoxic tumors after …
Stabilized and controlled release of radicals within copper formate-based nanozymes for biosensing
Fenton-like radical processes are widely utilized to explain catalytic mechanisms of
peroxidase-like nanozymes, which exhibit remarkable catalytic activity, cost-effectiveness …
peroxidase-like nanozymes, which exhibit remarkable catalytic activity, cost-effectiveness …
Polyphenol-assisted albumin-based biomineralization nanocarriers with NIR-II-targeted photothermal performance towards broad-spectrum radical scavenging
The oxidative stress is a state of imbalance in the body's oxidative balance, which can cause
or worsen many diseases. Several studies have focused on the direct scavenging of free …
or worsen many diseases. Several studies have focused on the direct scavenging of free …
LYC loaded ferritin nanoparticles for intracerebral delivery and the attenuation of neurodegeneration in D-gal-induced mice
X Xia, H Li, X Xu, C Wu, Z Wang, J Yi, G Zhao… - Biomaterials Advances, 2023 - Elsevier
Recombinant human H-ferritin nanocage (rHuHF) loaded with natural antioxidative
lycopene molecules (LYC) was successfully constructed for the first time, aiming to enrich …
lycopene molecules (LYC) was successfully constructed for the first time, aiming to enrich …