Metals to combat antimicrobial resistance
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …
Advances in antifungal drug development: an up-to-date mini review
The utility of clinically available antifungals is limited by their narrow spectrum of activity,
high toxicity, and emerging resistance. Antifungal drug discovery has always been a …
high toxicity, and emerging resistance. Antifungal drug discovery has always been a …
Advanced and biomedical applications of Schiff-base ligands and their metal complexes: A review
A Soroceanu, A Bargan - Crystals, 2022 - mdpi.com
Because of their importance in a variety of interdisciplinary study domains, Schiff-base
ligands have performed a significant role in the evolution of contemporary coordination …
ligands have performed a significant role in the evolution of contemporary coordination …
Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First In Vivo Experiments
There are currently fewer than 10 antifungal drugs in clinical development, but new fungal
strains that are resistant to most current antifungals are spreading rapidly across the world …
strains that are resistant to most current antifungals are spreading rapidly across the world …
Visualized Gallium/Lyticase‐Integrated Antifungal Strategy for Fungal Keratitis Treatment
Fungal keratitis has been one of the common corneal infections that causes blindness, but
an effective antifungal strategy remains a challenge. The exopolysaccharides both in the …
an effective antifungal strategy remains a challenge. The exopolysaccharides both in the …
A review on the antimicrobial assessment of triazole-azomethine functionalized frameworks incorporating transition metals
Antimicrobial resistance is a growing threat to global public health that calls for innovative
strategies to develop new methods of action against resistance to emerging infectious …
strategies to develop new methods of action against resistance to emerging infectious …
Manganese-based advanced nanoparticles for biomedical applications: future opportunity and challenges
Nanotechnology is the most promising technology to evolve in the last decade. Recent
research has shown that transition metal nanoparticles especially manganese (Mn)-based …
research has shown that transition metal nanoparticles especially manganese (Mn)-based …
[HTML][HTML] Repurposing antifungal drugs for cancer therapy
N Weng, Z Zhang, Y Tan, X Zhang, X Wei… - Journal of Advanced …, 2023 - Elsevier
Background Repurposing antifungal drugs in cancer therapy has attracted unprecedented
attention in both preclinical and clinical research due to specific advantages, such as safety …
attention in both preclinical and clinical research due to specific advantages, such as safety …
Beyond silver sulfadiazine: A dive into more than 50 years of research and development on metal complexes of sulfonamides in medicinal inorganic chemistry
JHB Nunes, DH Nakahata, PP Corbi… - Coordination Chemistry …, 2023 - Elsevier
Sulfonamides revolutionized the treatment and management of bacterial infections. Prontosil
was the very first synthetic antibacterial agent ever used in the clinics and its metabolite …
was the very first synthetic antibacterial agent ever used in the clinics and its metabolite …
[HTML][HTML] Cytotoxic urea Schiff base complexes for multidrug discovery as anticancer activity and low in vivo oral assessing toxicity
LM Aroua, AN Al-Hakimi, MAM Abdulghani… - Arabian Journal of …, 2022 - Elsevier
Novel mononuclear complexes 2–8 derived from hybrid Urea Schiff base HL were
synthesized using various metal Ni 2+, Fe 3+, Cu 2+, Co 2+, Mn 2+, Zn 2+, and Cr 3+. The …
synthesized using various metal Ni 2+, Fe 3+, Cu 2+, Co 2+, Mn 2+, Zn 2+, and Cr 3+. The …