Genetic basis for congenital heart disease: revisited: a scientific statement from the American Heart Association

ME Pierpont, M Brueckner, WK Chung, V Garg… - Circulation, 2018 - Am Heart Assoc
This review provides an updated summary of the state of our knowledge of the genetic
contributions to the pathogenesis of congenital heart disease. Since 2007, when the initial …

Heart failure in pediatric patients with congenital heart disease

RB Hinton, SM Ware - Circulation research, 2017 - Am Heart Assoc
Heart failure (HF) is a complex clinical syndrome resulting from diverse primary and
secondary causes and shared pathways of disease progression, correlating with substantial …

2018 ESC guidelines for the management of cardiovascular diseases during pregnancy: the task force for the management of cardiovascular diseases during …

V Regitz-Zagrosek, JW Roos-Hesselink… - European heart …, 2018 - academic.oup.com
not override in any way whatsoever the individual responsibility of health professionals to
make appropriate and accurate decisions in consideration of each patient's health condition …

[HTML][HTML] Genetics of congenital heart disease: a narrative review of recent advances and clinical implications

J Yasuhara, V Garg - Translational Pediatrics, 2021 - ncbi.nlm.nih.gov
Congenital heart disease (CHD) is the most common human birth defect and remains a
leading cause of mortality in childhood. Although advances in clinical management have …

[HTML][HTML] Drosophila Heart as a Model for Cardiac Development and Diseases

A Souidi, K Jagla - Cells, 2021 - mdpi.com
The Drosophila heart, also referred to as the dorsal vessel, pumps the insect blood, the
hemolymph. The bilateral heart primordia develop from the most dorsally located …

Current status and challenges in prenatal and neonatal screening, diagnosis, and management of congenital heart disease in China

Y Zhang, J Wang, J Zhao, G Huang, K Liu… - The Lancet Child & …, 2023 - thelancet.com
Congenital heart disease (CHD), a wide spectrum of diseases with varied outcomes, is the
most common congenital malformation worldwide. In this Series of three papers, we …

[HTML][HTML] The role of epigenetics in congenital heart disease

TB Lim, SYR Foo, CK Chen - Genes, 2021 - mdpi.com
Congenital heart disease (CHD) is the most common birth defect among newborns
worldwide and contributes to significant infant morbidity and mortality. Owing to major …

Evidence-based assessment of congenital heart disease genes to enable returning results in a genomic study

EL Griffin, SN Nees, SU Morton, J Wynn… - Circulation: Genomic …, 2023 - Am Heart Assoc
Background: Congenital heart disease (CHD) is the most common major congenital
anomaly and causes significant morbidity and mortality. Epidemiologic evidence supports a …

Genetic basis of human congenital heart disease

SN Nees, WK Chung - Cold Spring Harbor perspectives …, 2020 - cshperspectives.cshlp.org
Congenital heart disease (CHD) is the most common major congenital anomaly with an
incidence of∼ 1% of live births and is a significant cause of birth defect–related mortality …

Prevalence of noncardiac and genetic abnormalities in neonates undergoing cardiac operations: analysis of the society of thoracic surgeons congenital heart surgery …

A Patel, JM Costello, CL Backer, SK Pasquali… - The Annals of thoracic …, 2016 - Elsevier
Background Among patients with congenital heart disease (CHD), the coexistence of
noncardiac congenital anatomic abnormalities (NC), genetic abnormalities (GA), and …