The developing fetus requires substantial amounts of fatty acids to support rapid cellular
growth and activity. Although the fatty acid composition delivered to the fetus is largely …

The ovarian follicle luteinizing hormone (LH) signaling molecules that regulate oocyte
meiotic maturation have recently been identified. The LH signal reduces preovulatory follicle …

Reproductive aging in female mammals is an irreversible process associated with declining
oocyte quality, which is the rate-limiting factor to fertility. Here, we show that this loss of …

BACKGROUND While oocyte IVM is practiced sporadically it has not achieved widespread
clinical practice globally. However, recently there have been some seminal advances in our …

The conventional method of human oocyte maturation in vitro in the presence of
gonadotrophins continues to be a relatively low-success procedure in the assisted …

STUDY QUESTION Can a pre-in vitro maturation (pre-IVM) medium containing signaling
molecules rather than chemical/pharmaceutical agents, sustain meiotic arrest and improve …

Oocytes are maintained in a state of meiotic arrest following the first meiotic division until
ovulation is triggered. Within the antral follicle, meiotic arrest is actively suppressed in a …

The FecB gene has been discovered as an important gene in sheep for its high relationship
with the ovulation rate, but its regulatory mechanism remains unknown. In the present study …

The administration of follicle-stimulating hormone (FSH) prior to oocyte retrieval improves
oocyte developmental competence. During bovine embryo production in vitro, however …

Pre-maturation aging of immature oocytes may adversely affect the fate of an oocyte.
Oxidative stress is one of the most detrimental factors affecting oocyte developmental …