Health professionals are encouraged to take the ESC Guidelines fully into account when
exercising their clinical judgment, as well as in the determination and the implementation of …

Background and Purpose: Population-wide reductions in cardiovascular disease incidence
and mortality have not been shared equally by African Americans. The burden of …

Background Inability to tolerate statins because of muscle symptoms contributes to
uncontrolled cholesterol levels and insufficient cardiovascular risk reduction. Bempedoic …

Background Guidelines recommend exercise for cardiovascular health, although evidence
from trials linking exercise to cardiovascular health through intermediate biomarkers …

While risk scores are invaluable tools for adapted preventive strategies, a significant gap
exists between predicted and actual event rates. Additional tools to further stratify the risk of …

Objective 1) To synthesize the current observational evidence for the association between
sedentary behavior and health outcomes using information from systematic reviews. 2) To …

Context: Thyroid dysfunction is one of the leading endocrine disorders. Previous data show
that about half of the population with thyroid dysfunction remains undiagnosed. Objective …

HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …

Chronic diseases (ie, noncommunicable diseases), mainly cardiovascular disease, cancer,
respiratory diseases and type-2-diabetes, are now the leading cause of death, disability and …

Identification of subjects at increased risk for cardiovascular events plays a central role in the
worldwide efforts to improve prevention, prediction, diagnosis, and prognosis of …