[HTML][HTML] Hepatitis C virus: life cycle in cells, infection and host response, and analysis of molecular markers influencing the outcome of infection and response to …

LB Dustin, B Bartolini, MR Capobianchi… - Clinical microbiology and …, 2016 - Elsevier
Hepatitis C virus (HCV) is a major global health burden accounting for around 170 million
chronic infections worldwide. Since its discovery, which dates back to about 30 years ago …

Prospects for developing an Hepatitis C virus E1E2‐based nanoparticle vaccine

EA Toth, AK Andrianov… - Reviews in Medical …, 2023 - Wiley Online Library
Globally, more than 58 million people are chronically infected with Hepatitis C virus (HCV)
with 1.5 million new infections occurring each year. An effective vaccine for HCV is therefore …

Global control of hepatitis C virus

AL Cox - Science, 2015 - science.org
Hepatitis C virus (HCV) infection is a blood-borne disease that infects~ 185 million people (~
3% of the world's population) worldwide. It can result in severe liver disease and is the …

The epidemiology of hepatitis B and hepatitis C infections in China from 2004 to 2014: an observational population‐based study

Z Liu, Q Yang, O Shi, W Ye, X Chen… - Journal of Viral …, 2018 - Wiley Online Library
Viral hepatitis is a major public health concern in China, but data on national
epidemiological characteristics are lacking. We collected reporting incidence data on …

[HTML][HTML] Health care-associated hepatitis C virus infection

B Pozzetto, M Memmi, O Garraud, X Roblin… - World journal of …, 2014 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) is a blood-borne pathogen that has a worldwide distribution and
infects millions of people. Care-associated HCV infections represented a huge part of …

Hepatitis C virus vaccine candidates inducing protective neutralizing antibodies

C Fauvelle, CC Colpitts, Z Keck, BG Pierce… - Expert review of …, 2016 - Taylor & Francis
Introduction: With more than 150 million chronically infected people, hepatitis C virus (HCV)
remains a substantial global health burden. Direct-acting antivirals have dramatically …

Deconvolving mutational patterns of poliovirus outbreaks reveals its intrinsic fitness landscape

AA Quadeer, JP Barton, AK Chakraborty… - Nature …, 2020 - nature.com
Vaccination has essentially eradicated poliovirus. Yet, its mutation rate is higher than that of
viruses like HIV, for which no effective vaccine exists. To investigate this, we infer a fitness …

Antibody repertoire analysis of hepatitis C virus infections identifies immune signatures associated with spontaneous clearance

S Eliyahu, O Sharabi, S Elmedvi, R Timor… - Frontiers in …, 2018 - frontiersin.org
Hepatitis C virus (HCV) is a major public health concern, with over 70 million people infected
worldwide, who are at risk for developing life-threatening liver disease. No vaccine is …

Mutational escape of CD8+ T cell epitopes: implications for prevention and therapy of persistent hepatitis virus infections

J Timm, CM Walker - Medical microbiology and immunology, 2015 - Springer
Over the past two decades, much has been learned about how human viruses evade T cell
immunity to establish persistent infection. The lessons are particularly relevant to two …

Immunoglobulin with High-Titer In Vitro Cross-Neutralizing Hepatitis C Virus Antibodies Passively Protects Chimpanzees from Homologous, but Not Heterologous …

J Bukh, RE Engle, K Faulk, RY Wang, P Farci… - Journal of …, 2015 - Am Soc Microbiol
The importance of neutralizing antibodies (NAbs) in protection against hepatitis C virus
(HCV) remains controversial. We infused a chimpanzee with H06 immunoglobulin from a …