Innate immunity represents the semi-specific first line of defense and provides the initial host
response to tissue injury, trauma, and pathogens. Innate immunity activates the adaptive …

Psoriasis is a chronic systemic inflammatory disorder associated with several comorbidities
in addition to the characteristic skin lesions. Metabolic syndrome (MetS) is the most frequent …

The 2020 annual meeting for IOIBD was scheduled to occur in March, but was cancelled
owing to the emergence of COVID-19. Given how this disease might affect patients with IBD …

Background Ustekinumab is currently approved globally in Crohn's disease (CD) and
psoriatic diseases. Recent phase 3 data demonstrate safety/efficacy in ulcerative colitis …

Background Biologic therapies in patients with Crohn's disease often yield low clinical and
endoscopic remission rates. After multiple failed therapies, combining two biologic therapies …

The inflammatory bowel diseases (IBDs) are chronic immune-mediated inflammatory
disorders, including ulcerative colitis (UC) and Crohn's disease (CD). IBD results from a …

Background: Treatment of inflammatory bowel diseases (IBD) has tremendously improved
during the last 20 years; however, a substantial fraction of patients does not respond to …

Psoriasis, an inflammatory skin disease, and psoriatic arthritis (PsA), an inflammatory
arthritis, share clinical, genetic, and pathogenic factors and may be summed as one disease …

Background: Inflammatory bowel disease (IBD) is a chronic inflammatory disorder, primarily
of, but not restricted to, the gut. Association between IBD and cancer has been clearly …

Background Psoriasis treatments lack durable efficacy and have inconvenient
administration, highlighting the need for new therapies. Objective To evaluate the efficacy …