Long-acting drugs and formulations for the treatment and prevention of HIV infection

C Flexner, A Owen, M Siccardi, S Swindells - International journal of …, 2021 - Elsevier
Long-acting and extended-release formulations represent one of the most important
approaches to improving the treatment and prevention of chronic HIV infection. Long-acting …

Therapeutic review of cabotegravir/rilpivirine long‐acting antiretroviral injectable and implementation considerations at an HIV specialty clinic

ZW Howe, S Norman, AF Lueken… - … : The Journal of …, 2021 - Wiley Online Library
Abstract Cabotegravir/rilpivirine (CAB/RPV) was recently approved by the US Food and
Drug Administration (FDA) as the first complete parenteral antiretroviral (ART) regimen for …

[HTML][HTML] Factors associated with preferences for long-acting injectable antiretroviral therapy among adolescents and young people living with HIV in South Africa

E Toska, S Zhou, J Chen-Charles, L Gittings… - AIDS and Behavior, 2023 - Springer
Long-acting injectable anti-retroviral therapy (LAART) may overcome barriers to long-term
adherence and improve the survival of adolescents and young people living with HIV …

Multisite study of women living with HIV's perceived barriers to, and interest in, long-acting injectable antiretroviral therapy

MM Philbin, CL Parish, EN Kinnard… - JAIDS Journal of …, 2020 - journals.lww.com
Background: Adherence to antiretroviral therapy (ART) is imperative for viral suppression
and reducing HIV transmission, but many people living with HIV report difficultly sustaining …

[HTML][HTML] “A dream come true”: Perspectives on long-acting injectable antiretroviral therapy among female sex workers living with HIV from the Dominican Republic and …

D Kerrigan, T Sanchez Karver, O Muraleetharan… - PLoS …, 2020 - journals.plos.org
Background Long-acting injectable antiretroviral therapy (LA ART) was found to be non-
inferior to daily oral ART in Phase 3 clinical trials. LA ART may offer an important alternative …

Redefining therapeutic success in HIV patients: an expert view

A Antela, A Rivero, JM Llibre… - Journal of Antimicrobial …, 2021 - academic.oup.com
Thanks to advances in the field over the years, HIV/AIDS has now become a manageable
chronic condition. Nevertheless, a new set of HIV-associated complications has emerged …

Potential of long-acting products to transform the treatment and prevention of human immunodeficiency virus (HIV) in infants, children, and adolescents

EJ Abrams, E Capparelli, T Ruel… - Clinical Infectious …, 2022 - academic.oup.com
Long-acting antiretroviral products have the potential to transform human immunodeficiency
virus (HIV) prevention and treatment approaches in pediatric populations. Broadly …

Cabotegravir-rilpivirine: the first complete long-acting injectable regimen for the treatment of HIV-1 infection

SH Durham, EB Chahine - Annals of Pharmacotherapy, 2021 - journals.sagepub.com
Objective: To review the efficacy and safety of cabotegravir (CAB) with rilpivirine (RPV) in the
treatment of HIV-1 infection. Data Sources: A literature search was performed using PubMed …

[HTML][HTML] “It's only fatness, it doesn't kill”: a qualitative study on perceptions of weight gain from use of dolutegravir-based regimens in women living with HIV in Uganda

Y Alhassan, A Twimukye, T Malaba, L Myer, C Waitt… - BMC Women's …, 2022 - Springer
Background Dolutegravir (DTG)-based regimens have been recommended by the WHO as
the preferred first-line and second-line HIV treatment in all populations. Evidence suggests …

Cabotegravir: the first long-acting injectable for HIV preexposure prophylaxis

SH Durham, A Milam, D Waer… - Annals of …, 2023 - journals.sagepub.com
Objective Review the pharmacology, pharmacokinetics, efficacy, safety, and role of long-
acting injectable cabotegravir (CAB-LA) in HIV preexposure prophylaxis (PrEP). Data …