The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease

M Amidfar, J de Oliveira, E Kucharska, J Budni, YK Kim - Life sciences, 2020 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

Modifiable predictors of dementia in mild cognitive impairment: a systematic review and meta-analysis

C Cooper, A Sommerlad, CG Lyketsos… - American Journal of …, 2015 - Am Psychiatric Assoc
Objective: Public health campaigns encouraging early help seeking have increased rates of
mild cognitive impairment (MCI) diagnosis in Western countries, but we know little about …

Anxiety as a predictor for cognitive decline and dementia: a systematic review and meta-analysis

B Gulpers, I Ramakers, R Hamel, S Köhler… - The American Journal of …, 2016 - Elsevier
Background Because anxiety is postulated as a risk factor for dementia, we performed a
systematic review and meta-analysis to investigate whether anxiety predicts cognitive …

Mild cognitive impairment in geriatrics

EG Tangalos, RC Petersen - Clinics in geriatric medicine, 2018 - geriatric.theclinics.com
The concept of mild cognitive impairment (MCI) as an intermediate state between normal
cognition and dementia entered into the vernacular of geriatric medicine more than 30 years …

The neuropsychiatric inventory: development and applications

J Cummings - Journal of geriatric psychiatry and neurology, 2020 - journals.sagepub.com
Reasons for the Study: The Neuropsychiatric Inventory (NPI) has been used for studies of
neuropsychiatric symptoms in neurodegenerative disorders for the past 25 years. This article …

Late-life depression, mild cognitive impairment, and dementia: possible continuum?

F Panza, V Frisardi, C Capurso, A D'Introno… - The American Journal of …, 2010 - Elsevier
Clinical and epidemiologic research has focused on the identification of risk factors that may
be modified in predementia syndromes, at a preclinical and early clinical stage of dementing …

The association of neuropsychiatric symptoms in MCI with incident dementia and Alzheimer disease

PB Rosenberg, MM Mielke, BS Appleby, ES Oh… - The American Journal of …, 2013 - Elsevier
Objectives Individuals with mild cognitive impairment (MCI) are at high risk of developing
dementia and/or Alzheimer disease (AD). Among persons with MCI, depression and anxiety …

Neuropsychiatric symptoms in mild cognitive impairment: a literature review

E Martin, L Velayudhan - Dementia and Geriatric Cognitive Disorders, 2020 - karger.com
Background: Neuropsychiatric symptoms (NPS) in dementia have received much attention
due to their high prevalence and their significant implications. NPS in mild cognitive …

Management of behavioral problems in Alzheimer's disease

S Gauthier, J Cummings, C Ballard… - International …, 2010 - cambridge.org
Alzheimer's disease (AD) is a complex progressive brain degenerative disorder that has
effects on multiple cerebral systems. In addition to cognitive and functional decline, diverse …

A systematic review of neuropsychiatric symptoms in mild cognitive impairment

R Monastero, F Mangialasche… - Journal of …, 2009 - content.iospress.com
Mild cognitive impairment (MCI) is a clinical concept proposed as an intermediate state
between normal aging and dementia. This condition has multiple heterogeneous sources …