A generalized mechanism for hormetic dose responses is proposed that is based on the
redox-activated transcription factor (TF), Nrf2, and its upregulation of an integrative system of …

Hormesis is a favorable response to low level exposures to substance or to adverse
conditions. This phenomenon has become a target to achieve greater crop productivity. This …

Dose-response is the backbone of toxicology, and one of the most debated scientific issues
over the 20 th century. It was in the last century that the scientific community applauded the …

Numerous studies highlighted the beneficial effects of the Mediterranean diet (MD) in
maintaining health, especially during ageing. Even neurodegeneration, which is part of the …

The phrase “what doesn't kill us makes us stronger” suggests the possibility that living
systems have evolved a spectrum of adaptive mechanisms resulting in a biological stress …

An ever-expanding hormetic database (HDB) was used to demonstrate that the median
maximal hormetic stimulatory response (MHSR) of biphasic dose-response relationships …

Hormesis is a biphasic dose–response relationship with contrasting effects of low versus
high doses of stress. Hormesis is rapidly developing in plant science research and has wide …

Accumulation of metals by plants is an important area of investigation in plant ecology and
evolution as well as in soil contamination/phytoremediation practices. This paper reports that …

Rare earth elements (REEs) have recently received particular attention due to their
accumulation in the environment. Such heightened recognition prompted our evaluation of …

Emerging evidence indicates that the dysregulation of cellular redox homeostasis and
chronic inflammatory processes are implicated in the pathogenesis of kidney and brain …