Endothelial cells, which form the inner cellular lining of blood vessels and lymphatics,
display remarkable heterogeneity in structure and function. This is the second of a 2-part …

The endothelial cells play a crucial role in the progression of angiogenesis, which causes
cell re-modulation, proliferation, adhesion, migration, invasion and survival. Angiogenic …

To identify pathways involved in adult lung regeneration, we employ a unilateral
pneumonectomy (PNX) model that promotes regenerative alveolarization in the remaining …

Chronic obstructive pulmonary disease (COPD) is one of the most common causes of death
worldwide. We report in an emphysema model of mice chronically exposed to tobacco …

During the development of the pulmonary vasculature in the fetus, many structural and
functional changes occur to prepare the lung for the transition to air breathing. The …

Certain forms of hexavalent chromium [Cr (VI)] are known respiratory carcinogens that
induce a broad spectrum of DNA damage. Cr (VI)-carcinogenesis may be initiated or …

Chronic obstructive pulmonary diseases (COPD), comprised of pulmonary emphysema,
chronic bronchitis, and structural and inflammatory changes of small airways, is a leading …

The mechanisms involved in the genesis of chronic obstructive pulmonary disease (COPD)
are poorly defined. This area is complicated and difficult to model because COPD consists of …

Early life nutritional exposures, combined with changes in lifestyle in adult life, can result in
increased risk of chronic diseases. Although much of the focus on the developmental origins …

The population of infants at risk for retinopathy of prematurity (ROP) varies by world region;
in countries with well developed neonatal intensive care services, the highest risk infants are …