Abstract Low Club Cell 16 kDa protein (CC16) plasma levels are linked to accelerated lung
function decline in patients with chronic obstructive pulmonary disease (COPD). Cigarette …

Asthma is a chronic complex pulmonary disease characterized by airway inflammation,
remodeling, and hyperresponsiveness. Vascular endothelial growth factor (VEGF) and …

Emphysema is mainly caused by cigarette smoking and is characterized by the loss of
alveolar integrity and an enlargement of the alveolar space. However, mechanisms involved …

Pulmonary vascular diseases of the newborn comprise a wide range of pathological
conditions with developmental abnormalities in the pulmonary vasculature. Clinically …

Rationale: Chronic obstructive pulmonary disease is frequently complicated with
comorbidities, such as cardiovascular disease, osteoporosis, and body weight loss, but the …

The consequences of disturbed function of the pulmonary circulation remain an enigma to
most clinicians. There is disturbance of pulmonary circulatory function in nearly all cardiac …

Pulmonary hypertension (PH), increased blood pressure in the pulmonary arteries, is a
morbid and lethal disease. PH is classified into several groups based on etiology, but …

Idiopathic pulmonary hemosiderosis (IPH) is a rare disease that causes diffuse alveolar
hemorrhage (DAH). The latest data suggests an immunologic origin of IPH, and a new …

α1-Antitrypsin (A1AT) is a polyvalent, acute-phase reactant with an extensive range of
biological functions that go beyond those usually linked to its antiprotease (serpin) activities …

Purpose Antiangiogenic therapies targeting the vascular endothelial growth factor (VEGF)
pathway have yielded more modest clinical benefit to patients with non–small-cell lung …