Mitochondria are multifaceted organelles with key roles in anabolic and catabolic
metabolism, bioenergetics, cellular signalling and nutrient sensing, and programmed cell …

Energy metabolism in the brain has been considered one of the critical research areas of
neuroscience for ages. One of the most vital parts of brain metabolism cascades is lipid …

Mitochondrial diseases have a heterogeneous phenotype and can result from mutations in
the mitochondrial or nuclear genomes, constituting a diagnostically and therapeutically …

Multiple sclerosis (MS) is a demyelinating, degenerating disorder of the central nervous
system (CNS) that is accompanied by mitochondria energy production failure. A loss of …

As a requirement of aerobic metabolism, regulation of redox homeostasis is indispensable
for the continuity of living homeostasis and life. Since the stability of the redox state is …

TIMM50 is a core subunit of the TIM23 complex, the mitochondrial inner membrane
translocase responsible for the import of pre-sequence-containing precursors into the …

Since the early twentieth century, research on vitamins has revealed their therapeutic
potential beyond their role as essential micronutrients. Riboflavin, known as vitamin B2 …

Introduction: Inherited mitochondrial diseases are the most common group of metabolic
disorders caused by a defect in oxidative phosphorylation. They are characterized by a wide …

Simple Summary Neurodegenerative diseases are characterized by the progressive
degeneration of nerve cells. Some neurodegenerative diseases such as Alzheimer's and …

Mitochondria, well-known for years as the powerhouse and biosynthetic center of the cell,
are dynamic signaling organelles beyond their energy production and biosynthesis …