Cholesterol interactions with phospholipids in membranes

H Ohvo-Rekilä, B Ramstedt, P Leppimäki… - Progress in lipid …, 2002 - Elsevier
Mammalian cell membranes are composed of a complex array of glycerophospholipids and
sphingolipids that vary in head-group and acyl-chain composition. In a given cell type …

[HTML][HTML] Condensed complexes of cholesterol and phospholipids

HM McConnell, A Radhakrishnan - Biochimica et Biophysica Acta (BBA) …, 2003 - Elsevier
There is overwhelming evidence that lipid bilayer regions of animal cell membranes are in a
liquid state. Quantitative models of these bilayer regions must then be models of liquids …

Organization in lipid membranes containing cholesterol

SL Veatch, SL Keller - Physical review letters, 2002 - APS
A fundamental attribute of raft formation in cell membranes is lateral separation of lipids into
coexisting liquid phases. Using fluorescence microscopy, we observe spontaneous lateral …

Switchable nile red-based probe for cholesterol and lipid order at the outer leaflet of biomembranes

OA Kucherak, S Oncul, Z Darwich… - Journal of the …, 2010 - ACS Publications
Cholesterol and sphingomyelin form together a highly ordered membrane phase, which is
believed to play important biological functions in plasma membranes of mammalian cells …

[HTML][HTML] The condensing effect of cholesterol in lipid bilayers

WC Hung, MT Lee, FY Chen, HW Huang - Biophysical journal, 2007 - cell.com
The condensing effect of cholesterol on phospholipid bilayers was systematically
investigated for saturated and unsaturated chains, as a function of cholesterol concentration …

[HTML][HTML] The size of lipid rafts: an atomic force microscopy study of ganglioside GM1 domains in sphingomyelin/DOPC/cholesterol membranes

C Yuan, J Furlong, P Burgos, LJ Johnston - Biophysical journal, 2002 - cell.com
Atomic force microscopy has been used to study the distribution of ganglioside GM1 in
model membranes composed of ternary lipid mixtures that mimic the composition of lipid …

[HTML][HTML] Cholesterol-induced modifications in lipid bilayers: a simulation study

SW Chiu, E Jakobsson, RJ Mashl, HL Scott - Biophysical journal, 2002 - cell.com
We present analysis of new configurational bias Monte Carlo and molecular dynamics
simulation data for bilayers of dipalmitoyl phosphatidyl choline and cholesterol for …

Liquid-liquid immiscibility in membranes

HM McConnell, M Vrljic - Annual review of biophysics and …, 2003 - annualreviews.org
▪ Abstract The observation of liquid-liquid immiscibility in cholesterol-phospholipid mixtures
in monolayers and bilayers has opened a broad field of research into their physical …

Condensed complexes, rafts, and the chemical activity of cholesterol in membranes

A Radhakrishnan, TG Anderson… - Proceedings of the …, 2000 - National Acad Sciences
Epifluorescence microscopy studies of mixtures of phospholipids and cholesterol at the air–
water interface often exhibit coexisting liquid phases. The properties of these liquids point to …

[HTML][HTML] Condensed complexes of cholesterol and phospholipids

A Radhakrishnan, HM McConnell - Biophysical journal, 1999 - cell.com
Mixtures of dihydrocholesterol and phospholipids form immiscible liquids in monolayer
membranes at the air-water interface under specified conditions of temperature and 2 …