The effects of diet composition and chronic obesity on muscle growth and function

LGO de Sousa, AG Marshall… - Journal of Applied …, 2021 - journals.physiology.org
Diet-induced obesity (DIO) is associated with glucose intolerance, insulin resistance (IR),
and an increase in intramyocellular lipids (IMCL), which may lead to disturbances in glucose …

[HTML][HTML] Exercise training attenuates obesity-induced skeletal muscle remodeling and mitochondria-mediated apoptosis in the skeletal muscle

JW Heo, SZ Yoo, MH No, DH Park, JH Kang… - International journal of …, 2018 - mdpi.com
Obesity is characterized by the induction of skeletal muscle remodeling and mitochondria-
mediated apoptosis. Exercise has been reported as a positive regulator of skeletal muscle …

Gender‐specific differences in the development of sarcopenia in the rodent model of the ageing high‐fat rat

R Kob, C Fellner, T Bertsch, A Wittmann… - Journal of cachexia …, 2015 - Wiley Online Library
Background Sarcopenia is linked to functional impairments, loss of independence, and
mortality. In the past few years, obesity has been established as being a risk factor for a …

Fruit of Schisandra chinensis and its bioactive component schizandrin B ameliorate obesity-induced skeletal muscle atrophy

A Yoo, J Ahn, MJ Kim, HD Seo, JH Hahm… - Food Research …, 2022 - Elsevier
Schisandra chinensis fruit (Omiza in Korean), used for the production tea or liquor, and is
known to enhance skeletal muscle function. However, the effect of Omiza extract (OM) on …

[HTML][HTML] Gender-Specific Metabolomic Profiling of Obesity in Leptin-Deficient ob/ob Mice by 1H NMR Spectroscopy

EY Won, MK Yoon, SW Kim, Y Jung, HW Bae, D Lee… - PloS one, 2013 - journals.plos.org
Despite the numerous metabolic studies on obesity, gender bias in obesity has rarely been
investigated. Here, we report the metabolomic analysis of obesity by using leptin-deficient …

Time-restricted feeding combined with resistance exercise prevents obesity and improves lipid metabolism in the liver of mice fed a high-fat diet

R Damasceno de Lima… - American Journal …, 2023 - journals.physiology.org
Nonalcoholic fatty liver disease (NAFLD), a condition characterized by the accumulation of
fat in the liver, is estimated to be the most common liver disease worldwide. Obesity is a …

Beneficial effects of metformin on muscle atrophy induced by obesity in rats

MM Hasan, SM Shalaby, J El‐Gendy… - Journal of cellular …, 2019 - Wiley Online Library
Aim A growing interest to understand the signaling pathways mediating obesity‐induced
muscle atrophy is given. Metformin (Met) was reported to possess positive effects on …

[HTML][HTML] A short-term high-fat diet alters glutathione levels and IL-6 gene expression in oxidative skeletal muscles of young rats

DE Andrich, L Melbouci, Y Ou, N Auclair… - Frontiers in …, 2019 - frontiersin.org
Obesity and ensuing disorders are increasingly prevalent worldwide. High-fat diets (HFD)
and diet-induced obesity have been shown to induce oxidative stress and inflammation …

The influence of obesity and associated fatty acids on placental inflammation

AJ Eastman, RE Moore, SD Townsend, JA Gaddy… - Clinical …, 2021 - Elsevier
Purpose Maternal obesity, affecting nearly 1 in 4 pregnancies, is associated with increased
circulating saturated fatty acids, such as palmitate. These fatty acids are implicated in …

The effects of high fat diet and moderate exercise on TGFβ1 and collagen deposition in mouse skeletal muscle

Y Pincu, MA Linden, K Zou, T Baynard, MD Boppart - Cytokine, 2015 - Elsevier
Obesity is a primary cause of muscle insulin resistance and is also associated with
morphological and functional changes in the skeletal muscle including fibrosis. Studies …