The therapeutic potential of bone marrow mesenchymal stem cells in premature ovarian failure

Y He, D Chen, L Yang, Q Hou, H Ma, X Xu - Stem cell research & therapy, 2018 - Springer
With the development of regenerative medicine, a variety of mesenchymal stem cells
(MSCs) are increasingly considered for the treatment of premature ovarian failure (POF) …

Premature ovarian insufficiency: pathogenesis and therapeutic potential of mesenchymal stem cell

A Takahashi, A Yousif, L Hong, II Chefetz - Journal of Molecular Medicine, 2021 - Springer
Primary ovarian insufficiency (POI) is defined as a reduction in ovarian function before the
expected age of menopause. POI is known to increase the risk of cardiovascular disorders …

Transcriptome landscape of human folliculogenesis reveals oocyte and granulosa cell interactions

Y Zhang, Z Yan, Q Qin, V Nisenblat, HM Chang, Y Yu… - Molecular cell, 2018 - cell.com
The dynamic transcriptional regulation and interactions of human germlines and
surrounding somatic cells during folliculogenesis remain unknown. Using RNA sequencing …

Therapeutic effects of human umbilical cord mesenchymal stem cell-derived microvesicles on premature ovarian insufficiency in mice

Z Yang, X Du, C Wang, J Zhang, C Liu, Y Li… - Stem cell research & …, 2019 - Springer
Background Premature ovarian insufficiency (POI) is one of the leading causes of female
infertility, which is caused by an abnormal ovarian reserve. Currently, there is no effective …

[HTML][HTML] Vascular remodeling by placenta-derived mesenchymal stem cells restores ovarian function in ovariectomized rat model via the VEGF pathway

J Cho, TH Kim, J Seok, JH Jun, H Park, M Kweon… - Laboratory …, 2021 - Elsevier
Angiogenesis plays an important role in damaged organ or tissue and cell regeneration and
ovarian development and function. Primary ovarian insufficiency (POI) is a prevalent …

Current and future perspectives for improving ovarian tissue cryopreservation and transplantation outcomes for cancer patients

S Lee, S Ozkavukcu, SY Ku - Reproductive Sciences, 2021 - Springer
Although advances in cancer treatment and early diagnosis have significantly improved
cancer survival rates, cancer therapies can cause serious side effects, including ovarian …

Implications of nonphysiological ovarian primordial follicle activation for fertility preservation

J Grosbois, M Devos, I Demeestere - Endocrine reviews, 2020 - academic.oup.com
In recent years, ovarian tissue cryopreservation has rapidly developed as a successful
method for preserving the fertility of girls and young women with cancer or benign conditions …

[HTML][HTML] Advances in biomaterials and regenerative medicine for primary ovarian insufficiency therapy

S Zhang, D Zhu, X Mei, Z Li, J Li, M Xie, HJW Lutz… - Bioactive materials, 2021 - Elsevier
Primary ovarian insufficiency (POI) is an ovarian dysfunction that affects more than 1% of
women and is characterized by hormone imbalances that afflict women before the age of 40 …

The late effects of cancer treatment on female fertility and the current status of fertility preservation—a narrative review

KA Rodriguez-Wallberg, Y Jiang, T Lekberg… - Life, 2023 - mdpi.com
Fertility counseling should be offered to all individuals of young reproductive age early in the
patient's trajectory following a cancer diagnosis. Systemic cancer treatment and …

Research progress on the treatment of premature ovarian failure using mesenchymal stem cells: a literature review

J Wang, W Liu, D Yu, Z Yang, S Li… - Frontiers in Cell and …, 2021 - frontiersin.org
Premature ovarian failure (POF) has become one of the main causes of infertility in women
of childbearing age and the incidence of POF is increasing year by year, seriously affecting …