The putative role of neuroinflammation in the interaction between traumatic brain injuries, sleep, pain and other neuropsychiatric outcomes: a state-of-the-art review

A Herrero Babiloni, AA Baril… - Journal of clinical …, 2023 - mdpi.com
Sleep disturbances are widely prevalent following a traumatic brain injury (TBI) and have the
potential to contribute to numerous post-traumatic physiological, psychological, and …

Deplete and repeat: microglial CSF1R inhibition and traumatic brain injury

R Boland, ON Kokiko-Cochran - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Traumatic brain injury (TBI) is a public health burden affecting millions of people. Sustained
neuroinflammation after TBI is often associated with poor outcome. As a result, increased …

[HTML][HTML] The stress of losing sleep: Sex-specific neurobiological outcomes

CJ Wright, S Milosavljevic, A Pocivavsek - Neurobiology of stress, 2023 - Elsevier
Sleep is a vital and evolutionarily conserved process, critical to daily functioning and
homeostatic balance. Losing sleep is inherently stressful and leads to numerous detrimental …

Neuroprotective effect of Ziziphi Spinosae Semen on rats with p-chlorophenylalanine-induced insomnia via activation of GABAA receptor

F Xiao, S Shao, H Zhang, G Li, S Piao… - Frontiers in …, 2022 - frontiersin.org
Ziziphus jujuba var. spinosa (Bunge) Hu ex HF. Chow [Rhamnaceae; Ziziphi Spinosae
Semen (ZSS)] has attracted extensive attention as the first choice of traditional Chinese …

Exploring Astrocyte-Mediated Mechanisms in Sleep Disorders and Comorbidity

Y Li, M Que, X Wang, G Zhan, Z Zhou, X Luo, S Li - Biomedicines, 2023 - mdpi.com
Astrocytes, the most abundant cells in the brain, are integral to sleep regulation. In the
context of a healthy neural environment, these glial cells exert a profound influence on the …

[HTML][HTML] Trigeminal nerve stimulation restores hippocampal dopamine deficiency to promote cognitive recovery in traumatic brain injury

J Xu, S Wu, L Huo, Q Zhang, L Liu, Z Ye, J Cao… - Progress in …, 2023 - Elsevier
Cognitive impairment (CI) is a common neurological disease resulting from traumatic brain
injury (TBI). Trigeminal nerve stimulation (TNS) is an emerging, non-invasive, and effective …

Divergent spatial learning, enhanced neuronal transcription, and blood–brain barrier disruption develop during recovery from post-injury sleep fragmentation

ZM Tapp, C Ren, K Palmer, J Kumar, RR Atluri… - Neurotrauma …, 2023 - liebertpub.com
Traumatic brain injury (TBI) causes pathophysiology that may significantly decrease quality
of life over time. A major propagator of this response is chronic, maladaptive …

Activation of the Hippocampal DRD2 Alleviates Neuroinflammation, Synaptic Plasticity Damage and Cognitive Impairment After Sleep Deprivation

H Gao, Y Zhang, D Luo, J Xu, S Tan, Y Li, W Qi… - Molecular …, 2023 - Springer
Sleep loss is commonplace nowadays and profoundly impacts cognition. Dopamine
receptor D2 (DRD2) makes a specific contribution to cognition, although the precise …

Persistent hypersomnia following repetitive mild experimental traumatic brain injury: roles of chronic stress and sex differences

E Portillo, X Zi, Y Kim, LB Tucker, A Fu… - Journal of …, 2023 - Wiley Online Library
Traumatic brain injury (TBI) is often more complicated than a single head injury. An extreme
example of this point may be military service members who experience a spectrum of …

Multiparity differentially affects specific aspects of the acute neuroinflammatory response to traumatic brain injury in female mice

R Gilfarb, Z Tapp, E Lemanski, J Velasquez… - Neuroscience, 2023 - Elsevier
Pregnancy is associated with profound acute and long-term physiological changes, but the
effects of such changes on brain injury outcomes are unclear. Here, we examined the effects …