Malignant gliomas: current perspectives in diagnosis, treatment, and early response assessment using advanced quantitative imaging methods

R Ahmed, MJ Oborski, M Hwang… - Cancer management …, 2014 - Taylor & Francis
Malignant gliomas consist of glioblastomas, anaplastic astrocytomas, anaplastic
oligodendrogliomas and anaplastic oligoastrocytomas, and some less common tumors such …

Molecular imaging–based dose painting: A novel paradigm for radiation therapy prescription

SM Bentzen, V Gregoire - Seminars in radiation oncology, 2011 - Elsevier
Dose painting is the prescription of a nonuniform radiation dose distribution to the target
volume based on functional or molecular images shown to indicate the local risk of relapse …

Clinical applications of PET in brain tumors

W Chen - Journal of nuclear medicine, 2007 - Soc Nuclear Med
Malignant gliomas and metastatic tumors are the most common brain tumors. Neuroimaging
plays a significant role clinically. In low-grade tumors, neuroimaging is needed to evaluate …

Multimodality brain tumor imaging: MR imaging, PET, and PET/MR imaging

JR Fink, M Muzi, M Peck, KA Krohn - Journal of Nuclear Medicine, 2015 - Soc Nuclear Med
Standard MR imaging and CT are routinely used for anatomic diagnosis in brain tumors.
Pretherapy planning and posttreatment response assessments rely heavily on gadolinium …

PET/CT: Form and Function1

TM Blodgett, CC Meltzer, DW Townsend - Radiology, 2007 - pubs.rsna.org
Functional imaging with positron emission tomography (PET) is playing an increasingly
important role in the diagnosis and staging of malignant disease, image-guided therapy …

Imaging proliferation in brain tumors with 18F-FLT PET: comparison with 18F-FDG

W Chen, T Cloughesy, N Kamdar… - Journal of Nuclear …, 2005 - Soc Nuclear Med
3′-Deoxy-3′-18F-fluorothymidine (18F-FLT) is a recently developed PET tracer to image
tumor cell proliferation. We characterized 18F-FLT PET of brain gliomas and compared 18F …

Imaging proliferation in lung tumors with PET: 18F-FLT versus 18F-FDG

AK Buck, G Halter, H Schirrmeister… - Journal of nuclear …, 2003 - Soc Nuclear Med
Recently, the thymidine analog 3′-deoxy-3′-18F-fluorothymidine (FLT) was suggested for
imaging tumoral proliferation. In this prospective study, we examined whether 18F-FLT …

Predicting Treatment Response of Malignant Gliomas to Bevacizumab and Irinotecan by Imaging Proliferation With [18F] Fluorothymidine Positron Emission …

W Chen, S Delaloye, DHS Silverman… - Journal of Clinical …, 2007 - ascopubs.org
Purpose Evaluation of treatment effects in malignant brain tumors is challenging because of
the lack of reliable response predictors of tumor response. This study examines the …

[18F]FLT-PET in oncology: current status and opportunities

LB Been, AJH Suurmeijer, DCP Cobben… - European journal of …, 2004 - Springer
Abstract In recent years,[18 F]-fluoro-3′-deoxy-3′-L-fluorothymidine ([18 F] FLT) has been
developed as a proliferation tracer. Imaging and measurement of proliferation with PET …

[HTML][HTML] Correlation between Ki-67 immunohistochemistry and 18F-fluorothymidine uptake in patients with cancer: a systematic review and meta-analysis

A Chalkidou, DB Landau, EW Odell… - European journal of …, 2012 - Elsevier
BACKGROUND: Positron emission tomography (PET) imaging using the radiotracer 18F-
Fluorothymidine (FLT) has been proposed as an imaging biomarker of tumour proliferation …