Chronic myeloid leukemia provides an illustrative disease model for both molecular
pathogenesis of cancer and rational drug therapy. Chronic myeloid leukemia is a clonal …

Rapid developments have occurred both in laboratory medicine and in therapeutic
interventions for the management of patients with chronic myelogenous leukemia (CML) …

The BCR/ABL1 fusion gene is mainly caused by the t (9; 22)(q34; q11. 2) translocation,
which results in the Philadelphia (Ph) chromosome. The Ph chromosome is the typical …

This chapter deals with the application of fluorescence in situ hybridization (FISH) to study
interphase nuclei from patients with chronic myeloid leukemia (CML). In our experience …

Fluorescence in situ hybridization (FISH) continues to play an important role in clinical
investigations. Laboratories may create their own cutoff, a percentage of positive nuclei to …

Цель исследования: оценить эффективность и переносимость препарата гливек у
больных хроническим миелолейкозом после неудачной терапии препаратами …

Precursor B-lymphoblastic leukemia is typically surface immunoglobulin (sIg) negative.
Although rare cases of sIg+ precursor lymphoblastic leukemia are recognized, sIg+ …

Following therapy with imatinib (STI571) hematologic and cytogenetic response in chronic
myeloid leukemia (CML) is associated with conspicuous alterations of bone marrow (BM) …

[Therapeutic efficacy of imatinib mesylate (glivec) in chronic phase of myeloid leukemia]. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …

Цель исследования. Использование в клинической практике препарата гливек
(иматиниб мезилат, STI571), блокирующего активность онкобелка р210, позволяет …