[HTML][HTML] Advances and challenges in metatranscriptomic analysis

M Shakya, CC Lo, PSG Chain - Frontiers in genetics, 2019 - frontiersin.org
Sequencing-based analyses of microbiomes have traditionally focused on addressing the
question of community membership and profiling taxonomic abundance through amplicon …

[PDF][PDF] A simple guide to de novo transcriptome assembly and annotation

V Raghavan, L Kraft, F Mesny… - Briefings in …, 2022 - academic.oup.com
A transcriptome constructed from short-read RNA sequencing (RNA-seq) is an easily
attainable proxy catalog of protein-coding genes when genome assembly is unnecessary …

[HTML][HTML] Detection of early seeding of Richter transformation in chronic lymphocytic leukemia

F Nadeu, R Royo, R Massoni-Badosa… - Nature medicine, 2022 - nature.com
Richter transformation (RT) is a paradigmatic evolution of chronic lymphocytic leukemia
(CLL) into a very aggressive large B cell lymphoma conferring a dismal prognosis. The …

Genomic diversity of severe acute respiratory syndrome–coronavirus 2 in patients with coronavirus disease 2019

Z Shen, Y Xiao, L Kang, W Ma, L Shi… - Clinical infectious …, 2020 - academic.oup.com
Background A novel coronavirus (CoV), severe acute respiratory syndrome (SARS)–CoV-2,
has infected> 75 000 individuals and spread to> 20 countries. It is still unclear how fast the …

Non-syntrophic methanogenic hydrocarbon degradation by an archaeal species

Z Zhou, C Zhang, P Liu, L Fu, R Laso-Pérez, L Yang… - Nature, 2022 - nature.com
The methanogenic degradation of oil hydrocarbons can proceed through syntrophic
partnerships of hydrocarbon-degrading bacteria and methanogenic archaea,–. However …

Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study

LL Ren, YM Wang, ZQ Wu, ZC Xiang, L Guo… - Chinese medical …, 2020 - mednexus.org
Background: Human infections with zoonotic coronaviruses (CoVs), including severe acute
respiratory syndrome (SARS)-CoV and Middle East respiratory syndrome (MERS)-CoV …

Structure and function of the global topsoil microbiome

M Bahram, F Hildebrand, SK Forslund, JL Anderson… - Nature, 2018 - nature.com
Soils harbour some of the most diverse microbiomes on Earth and are essential for both
nutrient cycling and carbon storage. To understand soil functioning, it is necessary to model …

[HTML][HTML] Structure and function of the soil microbiome underlying N2O emissions from global wetlands

M Bahram, M Espenberg, J Pärn… - Nature …, 2022 - nature.com
Wetland soils are the greatest source of nitrous oxide (N2O), a critical greenhouse gas and
ozone depleter released by microbes. Yet, microbial players and processes underlying the …

The tomato pan-genome uncovers new genes and a rare allele regulating fruit flavor

L Gao, I Gonda, H Sun, Q Ma, K Bao, DM Tieman… - Nature …, 2019 - nature.com
Modern tomatoes have narrow genetic diversity limiting their improvement potential. We
present a tomato pan-genome constructed using genome sequences of 725 …

[HTML][HTML] Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2's q2-feature-classifier plugin

NA Bokulich, BD Kaehler, JR Rideout, M Dillon… - Microbiome, 2018 - Springer
Background Taxonomic classification of marker-gene sequences is an important step in
microbiome analysis. Results We present q2-feature-classifier (https://github. com/qiime2/q2 …