Ischemic stroke is a common issue that severely affects the human health. Between the
central nervous system and the enteric system, the" Gut-Brain" axis, the bidirectional …

Wushicha Granule, an over-the-counter-drug (OTC) prescription, consists of 19 traditional
Chinese herbals medicines (CHMs), such as Chaihu, Hongcha, Chuanxiong, Houpo, and …

Alzheimer's disease (AD) is the most common cause of neurodegenerative dementia and
one of the top medical concerns worldwide. Currently, the approved drugs to treat AD are …

Ethnopharmacological relevance Ischemic stroke (IS) has both high morbidity and mortality.
Previous research conducted by our group demonstrated that the bioactive ingredients of …

Cerebral ischemia/reperfusion causes exacerbated neuronal damage involving excessive
neuroinflammation and oxidative stress. ROS is considered a signal molecule to activate …

Zibushengfa Tablet is a widely consumed traditional Chinese medicine (TCM) prescription.
However, its main bioactives remain unclear and its pharmacopeia quality-marker (Q …

Background Neurovascular glial unit (NVGU) dysfunction has been reported to be an early
and critical event in the pathophysiology of Alzheimer's disease (AD) and vascular dementia …

Inflammation and metabolic disorders are crucial factors that induce type 2 diabetes mellitus
(T2DM). Lophatherum gracile Brongn.(L. gracile) has been popularly consumed as folk …

Context Jingchuan tablet (JCT) is a Chinese medicine prescription for treating ischaemic
cerebral stroke (ICS). However, its relevant mechanisms remain unclear. Objective To …

Introduction: Myocardial infarction (MI), the most prevalent ischemic heart disease,
constitutes a primary cause of global cardiovascular disease with incidence and mortality …