HCC-Related lncRNAs: roles and mechanisms

M Shah, D Sarkar - International journal of molecular sciences, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) presents a significant global health threat, particularly in
regions endemic to hepatitis B and C viruses, and because of the ongoing pandemic of …

LncRNAs and PTEN/PI3K signaling: A symphony of regulation in cancer biology

WH Almalki - Pathology-Research and Practice, 2023 - Elsevier
Abstract The Emergence of Long Non-coding RNAs (lncRNAs) as Key Regulators in Diverse
Biological Processes: A Paradigm Shift in Understanding Gene Expression and its Impact on …

[HTML][HTML] miRNA and lncRNA as potential tissue biomarkers in hepatocellular carcinoma

VR Mallela, M Rajtmajerová, A Trailin, V Liška… - Non-coding RNA …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is primary liver cancer, frequently diagnosed at advanced
stages with limited therapeutic options. MicroRNAs (miRNAs) regulate target gene …

Cooperative STAT3-NFkB signaling modulates mitochondrial dysfunction and metabolic profiling in hepatocellular carcinoma

S Ishteyaque, G Singh, KS Yadav, S Verma… - Metabolism, 2024 - Elsevier
Background Hepatocellular carcinoma (HCC) continues to pose a significant health
challenge and is often diagnosed at advanced stages. Metabolic reprogramming is a …

Long non‑coding RNAs, lipid metabolism and cancer

ZD Zhang, XR Hou, XL Cao… - Experimental and …, 2023 - spandidos-publications.com
Cancer has emerged as the most common cause of death in China. The change in lipid
metabolism has been confirmed to have a role in several tumor types, such as esophageal …

[HTML][HTML] The role of lncRNA-mediated ceRNA regulatory networks in liver fibrosis

J Jiang, I Gareev, T Ilyasova, A Shumadalova… - Non-coding RNA …, 2024 - Elsevier
In the dynamic realm of molecular biology and biomedical research, the significance of long
non-coding RNAs (lncRNAs) acting as competing endogenous RNAs (ceRNAs) continues to …

Nanotherapeutic approaches for delivery of long non-coding RNAs: an updated review with emphasis on cancer

F Davodabadi, S Mirinejad, S Malik, A Dhasmana… - Nanoscale, 2024 - pubs.rsc.org
The long noncoding RNAs (lncRNAs) comprise a wide range of RNA species whose length
exceeds 200 nucleotides, which regulate the expression of genes and cellular functions in a …

[HTML][HTML] A Novel Cholesterol Metabolism-Related lncRNA Signature Predicts the Prognosis of Patients with Hepatocellular Carcinoma and Their Response to …

H Lei, T Xiang, H Zhu, X Hu - Frontiers in Bioscience-Landmark, 2024 - imrpress.com
Background: The survival rate of hepatocellular carcinoma (HCC) is low and the prognosis
is poor. Metabolic reprogramming is still an emerging hallmark of cancer, and …

[HTML][HTML] LINC01134: a pivotal oncogene with promising predictive maker and therapeutic target in hepatocellular carcinoma

Y Yu, J Wang, Q Guo, H Luo - Frontiers in Oncology, 2024 - frontiersin.org
Hepatocellular carcinoma (HCC) represents a leading and fatal malignancy within the
gastrointestinal tract. Recent advancements highlight the pivotal role of long non-coding …

Molecular Mechanisms in Tumorigenesis of Hepatocellular Carcinoma and in Target Treatments—An Overview

RM Szilveszter, M Muntean, A Florea - Biomolecules, 2024 - mdpi.com
Hepatocellular carcinoma is the most common primary malignancy of the liver, with
hepatocellular differentiation. It is ranked sixth among the most common cancers worldwide …