[HTML][HTML] Role of cholinergic signaling in Alzheimer's disease

ZR Chen, JB Huang, SL Yang, FF Hong - Molecules, 2022 - mdpi.com
Acetylcholine, a neurotransmitter secreted by cholinergic neurons, is involved in signal
transduction related to memory and learning ability. Alzheimer's disease (AD), a progressive …

Neurotransmitter systems in the etiology of major neurological disorders: Emerging insights and therapeutic implications

M Nimgampalle, H Chakravarthy, S Sharma… - Ageing Research …, 2023 - Elsevier
Neurotransmitters serve as chemical messengers playing a crucial role in information
processing throughout the nervous system, and are essential for healthy physiological and …

[HTML][HTML] Bioavailability of hesperidin and its aglycone hesperetin—compounds found in citrus fruits as a parameter conditioning the pro-health potential …

K Wdowiak, J Walkowiak, R Pietrzak, A Bazan-Woźniak… - Nutrients, 2022 - mdpi.com
Hesperidin and hesperetin are polyphenols that can be found predominantly in citrus fruits.
They possess a variety of pharmacological properties such as neuroprotective and …

Bioactive compounds and their derivatives: an insight into prospective phytotherapeutic approach against alzheimer's disease

F Islam, JF Khadija, M Harun-Or-Rashid… - Oxidative Medicine …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a common neurodegenerative brain disorder that causes
cellular response alterations, such as impaired cholinergic mechanism, amyloid‐beta (Aβ) …

[HTML][HTML] Cholinergic dysfunction in COVID-19: frantic search and hoping for the best

EH Nadwa, HM Al-Kuraishy, AI Al-Gareeb… - Naunyn-Schmiedeberg's …, 2023 - Springer
A novel coronavirus known as severe acute respiratory syndrome coronavirus type 2 (SARS-
CoV-2) is a potential cause of acute respiratory infection called coronavirus disease 2019 …

[HTML][HTML] An overview of 1, 2, 3-triazole-containing hybrids and their potential anticholinesterase activities

SA Khan, MJ Akhtar, U Gogoi, DU Meenakshi, A Das - Pharmaceuticals, 2023 - mdpi.com
Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in
learning, memory, stress responses, and cognitive functioning. It is hydrolyzed into choline …

[HTML][HTML] Cholinergic receptor binding in unimpaired older adults, mild cognitive impairment, and Alzheimer's disease dementia

DL Sultzer, AC Lim, HL Gordon, BC Yarns… - Alzheimer's research & …, 2022 - Springer
Background Cholinergic neurotransmitter system dysfunction contributes to cognitive
impairment in Alzheimer's disease and other syndromes. However, the specific cholinergic …

Neurotoxicities induced by micro/nanoplastics: A review focusing on the risks of neurological diseases

S Liu, Y He, J Yin, Q Zhu, C Liao, G Jiang - Journal of Hazardous Materials, 2024 - Elsevier
Pollution of micro/nano-plastics (MPs/NPs) is ubiquitously prevalent in the environment,
leading to an unavoidable exposure of the human body. Despite the protection of the blood …

Recent advancement in therapeutic strategies for Alzheimer's disease: Insights from clinical trials

T Khan, R Waseem, M Shahid, J Ansari… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia, characterized by the
presence of plaques of amyloid beta and Tau proteins. There is currently no permanent cure …

Targeting the M1 muscarinic acetylcholine receptor in Alzheimer's disease

L Dwomoh, GS Tejeda, AB Tobin - Neuronal Signaling, 2022 - portlandpress.com
Alzheimer's disease (AD) remains a major cause of morbidity and mortality worldwide, and
despite extensive research, only a few drugs are available for management of the disease …