Targeting PI3K/Akt signal transduction for cancer therapy
Y He, MM Sun, GG Zhang, J Yang, KS Chen… - Signal transduction and …, 2021 - nature.com
Abstract The phosphatidylinositol 3-kinase (PI3K)/Akt pathway plays a crucial role in various
cellular processes and is aberrantly activated in cancers, contributing to the occurrence and …
cellular processes and is aberrantly activated in cancers, contributing to the occurrence and …
Metal-based photosensitizers as inducers of regulated cell death mechanisms
Y Zhang, BT Doan, G Gasser - Chemical Reviews, 2023 - ACS Publications
Over the last few decades, various forms of regulated cell death (RCD) have been
discovered and were found to improve cancer treatment. Although there are several reviews …
discovered and were found to improve cancer treatment. Although there are several reviews …
Oncolytic virotherapy: basic principles, recent advances and future directions
D Lin, Y Shen, T Liang - Signal transduction and targeted therapy, 2023 - nature.com
Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they
are generally considered to have direct oncolysis and cancer immune effects. With the …
are generally considered to have direct oncolysis and cancer immune effects. With the …
Harnessing nanomaterials for cancer sonodynamic immunotherapy
Immunotherapy has made remarkable strides in cancer therapy over the past decade.
However, such emerging therapy still suffers from the low response rates and immune …
However, such emerging therapy still suffers from the low response rates and immune …
[HTML][HTML] Cell death due to electroporation–a review
TB Napotnik, T Polajžer, D Miklavčič - Bioelectrochemistry, 2021 - Elsevier
Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …
permeability through membrane electroporation. Electroporation can be reversible and is …
Organometallic anti-tumor agents: targeting from biomolecules to dynamic bioprocesses
The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …
complexes could play a more significant role in human cancer therapy. However, targeting …
Programmed cell death detection methods: a systematic review and a categorical comparison
S Kari, K Subramanian, IA Altomonte, A Murugesan… - Apoptosis, 2022 - Springer
Programmed cell death is considered a key player in a variety of cellular processes that
helps to regulate tissue growth, embryogenesis, cell turnover, immune response, and other …
helps to regulate tissue growth, embryogenesis, cell turnover, immune response, and other …
Nickel: Human health and environmental toxicology
G Genchi, A Carocci, G Lauria, MS Sinicropi… - International journal of …, 2020 - mdpi.com
Nickel is a transition element extensively distributed in the environment, air, water, and soil.
It may derive from natural sources and anthropogenic activity. Although nickel is ubiquitous …
It may derive from natural sources and anthropogenic activity. Although nickel is ubiquitous …
Imbalanced GSH/ROS and sequential cell death
T Liu, L Sun, Y Zhang, Y Wang… - Journal of Biochemical …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are produced in cells during metabolic processes.
Excessive intracellular ROS may react with large biomolecules, such as DNA, RNA …
Excessive intracellular ROS may react with large biomolecules, such as DNA, RNA …
[HTML][HTML] Myricetin: A review of the most recent research
X Song, L Tan, M Wang, C Ren, C Guo, B Yang… - Biomedicine & …, 2021 - Elsevier
Myricetin (MYR) is a flavonoid compound widely found in many natural plants including
bayberry. So far, MYR has been proven to have multiple biological functions and it is a …
bayberry. So far, MYR has been proven to have multiple biological functions and it is a …