Overweight and obesity during pregnancy have been associated with increased birth
weight, childhood obesity, and noncommunicable diseases in the offspring, leading to a …

The developing fetus undergoes a dynamic period of rapid growth that is responsive to
changes in the in utero environment that may contribute to the development of fetal growth …

Abstract The goal of Working Group 1 in the Breastmilk Ecology: Genesis of Infant Nutrition
(BEGIN) Project was to outline factors influencing biological processes governing human …

Converging evidence from clinical and preclinical studies suggests that fetal vulnerability to
adverse prenatal exposures increases the risk for neuropsychiatric diseases such as autism …

Deficiency of decidual NK (dNK) cell number and function has been widely regarded as an
important cause of spontaneous abortion. However, the metabolic mechanism underlying …

Obesity is an increasing global health epidemic that affects all ages, including women of
reproductive age. During pregnancy, maternal obesity is associated with adverse pregnancy …

Understanding the developmental origins of health and disease is integral to overcome the
global tide of obesity and its metabolic consequences, including atherosclerotic …

Obesity is a chronic condition associated with dyslipidemia and insulin resistance. Here, we
show that the offspring of obese mothers are dyslipidemic and insulin resistant from the …

Metabolic changes in pregnant women begin in the first weeks after conception under the
influence of placental hormones that affect the metabolism of all nutrients. An increased …

Environment around conception can influence the developmental programme with lasting
effects on gestational and postnatal phenotype and with consequences for adult health and …