Genetics of obsessive-compulsive disorder

B Mahjani, K Bey, J Boberg, C Burton - Psychological medicine, 2021 - cambridge.org
BackgroundObsessive-compulsive disorder (OCD) is a psychiatric disorder with multiple
symptom dimensions (eg contamination, symmetry). OCD clusters in families and decades …

Toward a neurocircuit-based taxonomy to guide treatment of obsessive–compulsive disorder

E Shephard, ER Stern, OA van den Heuvel… - Molecular …, 2021 - nature.com
An important challenge in mental health research is to translate findings from cognitive
neuroscience and neuroimaging research into effective treatments that target the …

[HTML][HTML] Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression

S Larivière, J Royer, R Rodríguez-Cruces… - Nature …, 2022 - nature.com
Epilepsy is associated with genetic risk factors and cortico-subcortical network alterations,
but associations between neurobiological mechanisms and macroscale connectomics …

Brain structure in acutely underweight and partially weight-restored individuals with anorexia nervosa: A coordinated analysis by the ENIGMA eating disorders …

E Walton, F Bernardoni, VL Batury, K Bahnsen… - Biological …, 2022 - Elsevier
Background The pattern of structural brain abnormalities in anorexia nervosa (AN) is still not
well understood. While several studies report substantial deficits in gray matter volume and …

Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11. 2 deletion syndrome: a review of ENIGMA …

EJ Cheon, CE Bearden, D Sun… - Psychiatry and …, 2022 - Wiley Online Library
This review compares the main brain abnormalities in schizophrenia (SZ), bipolar disorder
(BD), major depressive disorder (MDD), and 22q11. 2 Deletion Syndrome (22q11DS) …

Fear conditioning and extinction in obsessive-compulsive disorder: a systematic review

SE Cooper, JE Dunsmoor - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Laboratory experiments using fear conditioning and extinction protocols help lay the
groundwork for designing, testing, and optimizing innovative treatments for anxiety-related …

ENIGMA HALFpipe: interactive, reproducible, and efficient analysis for resting‐state and task‐based fMRI data

L Waller, S Erk, E Pozzi, YJ Toenders… - Human Brain …, 2022 - Wiley Online Library
The reproducibility crisis in neuroimaging has led to an increased demand for standardized
data processing workflows. Within the ENIGMA consortium, we developed HALFpipe (H …

The enhancing NeuroImaging genetics through meta‐analysis consortium: 10 Years of global collaborations in human brain mapping

PM Thompson, N Jahanshad, L Schmaal… - Human brain …, 2022 - Wiley Online Library
Abstract This Special Issue of Human Brain Mapping is dedicated to a 10‐year anniversary
of the Enhancing NeuroImaging Genetics through Meta‐Analysis (ENIGMA) Consortium. It …

[HTML][HTML] Insulin and disorders of behavioural flexibility

M Sullivan, F Fernandez-Aranda… - Neuroscience & …, 2023 - Elsevier
Behavioural inflexibility is a symptom of neuropsychiatric and neurodegenerative disorders
such as Obsessive-Compulsive Disorder, Autism Spectrum Disorder and Alzheimer's …

[HTML][HTML] A systematic review of a polyvagal perspective on embodied contemplative practices as promoters of cardiorespiratory coupling and traumatic stress recovery …

A Poli, A Gemignani, F Soldani, M Miccoli - International Journal of …, 2021 - mdpi.com
Baseline respiratory sinus arrhythmia (RSA) has been proposed as a transdiagnostic
biomarker of stress vulnerability across psychopathologies, and a reliable association …