Neonatal abstinence syndrome is defined by signs and symptoms of withdrawal that infants
develop after intrauterine maternal drug exposure. All infants with documented in utero …

Abstract Purpose of Review Perinatal opioid use is a major public health problem and is
associated with a number of deleterious maternal and fetal effects. We review recent …

A significant number of advances have been made in the last 5 years with respect to the
identification, diagnosis, assessment, and management of infants with prenatal opioid …

Of the nearly 3.8 million infants born in the United States in 2018, 8.3% had low birth weight
(< 2500 g [5.5 lb]) and 10% were born preterm (gestational age of< 37 completed weeks) …

Physiologically-based pharmacokinetic (PBPK) modeling has emerged as a useful tool to
study pharmacokinetics (PK) in special populations, such as pregnant women, fetuses, and …

Background Neonatal abstinence syndrome (NAS) rates have dramatically increased.
Breastfeeding is a nonpharmacological intervention that may be beneficial, reducing NAS …

The opioid epidemic led to an increase in the number of neonatal opioid withdrawal
syndrome (NOWS) cases in infants born to opioid-dependent mothers. Hallmark features of …

Objective This study examines the associations of substance use disorders in pregnancy
with a set of neonatal outcomes. Methods This is a quantitative retrospective study. Three …

Objective The practice of rooming-in for opioid-dependent infants was introduced as the
standard of care at our hospital following a pilot study which demonstrated that such infants …

The opioid crisis was a recognized threat to public health in the United States since 2009
when annual deaths due to opioid overdose surpassed motor vehicle accidents. 1 …