Anatomic versus physiologic assessment of coronary artery disease: role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging …

KL Gould, NP Johnson, TM Bateman… - Journal of the American …, 2013 - jacc.org
Angiographic severity of coronary artery stenosis has historically been the primary guide to
revascularization or medical management of coronary artery disease. However, physiologic …

Does coronary flow trump coronary anatomy?

KL Gould - JACC: Cardiovascular Imaging, 2009 - jacc.org
Coronary function versus anatomy, flow versus stenosis: which optimizes coronary artery
disease (CAD) management? In patients, coronary flow is poorly related to stenosis severity …

Prognostic value of stress myocardial perfusion positron emission tomography: results from a multicenter observational registry

S Dorbala, MF Di Carli, RS Beanlands… - Journal of the American …, 2013 - jacc.org
Objectives: The primary objective of this multicenter registry was to study the prognostic
value of positron emission tomography (PET) myocardial perfusion imaging (MPI) and the …

Incremental prognostic value of gated Rb-82 positron emission tomography myocardial perfusion imaging over clinical variables and rest LVEF

S Dorbala, R Hachamovitch, Z Curillova… - JACC: Cardiovascular …, 2009 - jacc.org
Objectives: This investigation sought to study the incremental value of gated rubidium (Rb)-
82 positron emission tomography (PET) myocardial perfusion imaging (MPI) over clinical …

Impact of unexpected factors on quantitative myocardial perfusion and coronary flow reserve in young, asymptomatic volunteers

S Sdringola, NP Johnson, RL Kirkeeide, E Cid… - JACC: Cardiovascular …, 2011 - jacc.org
Objectives: We sought to quantify ranges of normal myocardial perfusion and flow reserve in
young, asymptomatic volunteers after systematic historical and laboratory screening for …

Quantification of myocardial blood flow with 82Rb positron emission tomography: clinical validation with 15O-water

JO Prior, G Allenbach, I Valenta, M Kosinski… - European journal of …, 2012 - Springer
Purpose Quantification of myocardial blood flow (MBF) with generator-produced 82 Rb is an
attractive alternative for centres without an on-site cyclotron. Our aim was to validate 82 Rb …

Prognostic value of PET myocardial perfusion imaging in obese patients

BJW Chow, S Dorbala, MF Di Carli, ME Merhige… - JACC: Cardiovascular …, 2014 - jacc.org
Objectives: This study sought to determine and compare the prognostic and incremental
value of positron emission tomography (PET) in normal, overweight, and obese patients …

Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularization

R Kones - Vascular Health and Risk Management, 2010 - Taylor & Francis
The objectives in treating angina are relief of pain and prevention of disease progression
through risk reduction. Mechanisms, indications, clinical forms, doses, and side effects of the …

PET assessment of myocardial perfusion reserve inversely correlates with intravascular ultrasound findings in angiographically normal cardiac transplant recipients

YW Wu, YH Chen, SS Wang, HY Jui… - Journal of Nuclear …, 2010 - Soc Nuclear Med
Cardiac allograft vasculopathy (CAV) is the major determinant of long-term survival after
heart transplantation. We aimed to evaluate the efficacy of PET as a noninvasive way to …

Myocardial blood flow: Putting it into clinical perspective

TH Schindler - Journal of Nuclear Cardiology, 2016 - Elsevier
In recent years, positron emission tomography/computed tomography (PET/CT)-determined
myocardial perfusion in conjunction with myocardial blood flow (MBF) quantification in mL …