Altered metabolic patterns in tumor cells not only meet their own growth requirements but
also shape an immunosuppressive microenvironment through multiple mechanisms …

Accelerating cases of diabetes worldwide have given rise to higher incidences of diabetic
complications. MiRNAs, a much-explored class of non-coding RNAs, play a significant role …

Background Previous studies have confirmed that the microglial activation and subsequent
inflammatory responses in the trigeminal nucleus caudalis (TNC) are involved in the central …

Diabetic peripheral neuropathy (DPN) is a major complication of diabetes mellitus with a
high incidence. Oxidative stress, which is a crucial pathophysiological pathway of DPN, has …

Abstract Treatment for chronic diabetic foot ulcers is limited by the inability to simultaneously
address the excessive inflammation and impaired re-epithelization and remodeling …

Abstract Background Non‐coding RNAs (ncRNAs) are involved in neuropathic pain
development. Herein, we systematically searched for neuropathic pain‐related ncRNAs …

Neuropathic pain represents one of the most common complications associated with
diabetes mellitus (DM) that impacts quality of life. Accumulating studies have highlighted the …

Abstract The sodium channel 1.7 (Nav1. 7), which is encoded by SCN9A gene, is involved in
neuropathic pain. As crucial regulators of gene expression, many miRNAs have already …

Introduction MicroRNAs play a key role in neuropathic pain. In a previous study, miR-190a-
5p was significantly downregulated in diabetic neuropathic pain (DNP). However, the role …

Nitric oxide (NO)/cyclic guanosine 3′, 5′-monophosphate (cGMP) signaling has been
shown to act as a mediator involved in pain transmission and processing. In this review, we …