Estrogen affects proliferation and migration of different skin components, thus influencing
wound healing processes. The human keratinocyte cell line NCTC 2544 has been used to …

Metformin improves cardiovascular prognosis in patients with diabetes mellitus, compared to
alternative glucose-lowering drugs, despite similar glycemic control. Direct cardiovascular …

Incretins are gastrointestinal‐derived hormones released in response to a meal playing a
key role in the regulation of postprandial secretion of insulin (incretin effect) and glucagon by …

Sodium-glucose cotransporter 2 inhibitor (SGLT2-i) effects on cardiac ischemia/reperfusion
(I/R) injury are unclear. Unlike SGLT2-i, dipeptidyl peptidase 4 inhibitors (DPP4-i) have …

Doxorubicin is an effective chemotherapeutic drug, but causes cardiotoxicity which limits its
use. Oxidative stress, mitochondrial dysfunction, and inflammation are closely implicated in …

Background Metformin has long been used for glycemic control in diabetic state. Recently,
other benefits of metformin beyond blood glucose regulation have emerged. Objectives To …

In the present study we have used hypopituitary Ames dwarf mice, which lack GH, prolactin
and TSH, to investigate the consequences of the deficiency of these hormones on glucose …

Cardiac autonomic imbalance including sympathetic overactivity and diminished
parasympathetic activity is associated with left ventricular (LV) dysfunction in cases of …

Aim To explore the chronic effects of metformin on testosterone levels in men with type 2
diabetes mellitus (T2DM). Methods This is a secondary analysis of a real-world study …

Altered cardiac mitochondrial dynamics with excessive fission is a predominant cause of
cardiac dysfunction during ischemia/reperfusion (I/R) injury. Although pre-ischemic inhibition …