Current prevalence of HTLV‐1 in Japan as determined by screening of blood donors

M Satake, K Yamaguchi… - Journal of medical …, 2012 - Wiley Online Library
The human T-lymphotropic virus type 1 (HTLV-1; Retroviridae, Deltaretrovirus, Simian T
lymphotropic virus) is a pathogenic retrovirus that causes adult T-cell leukemia, HTLV-1 …

Key issues in the diagnosis and treatment of multiple sclerosis: an overview

P O'Connor - Neurology, 2002 - AAN Enterprises
Key issues in the diagnosis and treatment of multiple sclerosis | Neurology Skip to main content
Skip to main content AAN.com AAN Publications Author Center About the Journals Press …

Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.

WJ Grossman, JT Kimata, FH Wong… - Proceedings of the …, 1995 - National Acad Sciences
The human T-cell leukemia virus type I Tax protein trans-activates several cellular genes
implicated in T-cell replication and activation. To investigate its leukemogenic potential, Tax …

The tat Gene of Human T-Lymphotropic Virus Type 1 Induces Mesenchymal Tumors in Transgenic Mice

M Nerenberg, SH Hinrichs, RK Reynolds, G Khoury… - Science, 1987 - science.org
Human T-lymphotropic virus type 1 (HTLV-1) is a suspected causative agent of adult T-cell
leukemia. One of the viral genes encodes a protein (tat) that not only results in …

Time to eradicate HTLV-1: an open letter to WHO

F Martin, Y Tagaya, R Gallo - The Lancet, 2018 - thelancet.com
Human T-cell leukaemia virus 1 (HTLV-1) is the most potent carcinogenic oncovirus and
potentially the most oncogenic risk factor including chem ical carcinogens. 1 A unique and …

HTLV-1 and polymyositis in Jamaica

OS Morgan, C Mora, P Rodgers-Johnson, G Char - The Lancet, 1989 - Elsevier
IgG antibodies to human T-cell lymphotropic virus (HTLV-1) were found in 11 of 13 (85%)
Jamaican patients with idiopathic adult polymyositis. The association was first observed in 7 …

Chronic progressive myelopathy associated with elevated antibodies to human T‐lymphotropic virus type I and adult T‐cell leukemialike cells

M Osame, M Matsumoto, K Usuku… - Annals of Neurology …, 1987 - Wiley Online Library
Six adult patients had a chronic progressive myelopathy that possessed the following
features:(1) high antibody titers to human T‐lymphotropic virus type I (HTLV‐I) in serum and …

HTLV‐I uveitis: a distinct clinical entity caused by HTLV‐I

M Mochizuki, T Watanabe, K Yamaguchi… - Japanese Journal of …, 1992 - Wiley Online Library
Seroepidemiological, clinical and virological studies were carried out in an HTLV‐I endemic
area to find out if HTLV‐I caused an intraocular inflammatory disorder, uveitis. The …

Sexual transmission of human T-lymphotropic virus type I (HTLV-I)

EL Murphy, JP Figueroa, WN Gibbs… - Annals of internal …, 1989 - acpjournals.org
Study Objective: To study the seroprevalence of human T-lymphotropic virus type I (HTLV-I)
in a sexually active population and to determine sexual behavior risk factors for infection …

Heterogeneous geographic distribution of human T-cell lymphotropic viruses I and II (HTLV-I/II): serological screening prevalence rates in blood donors from large …

B Catalan-Soares, ABF Carneiro-Proietti… - Cadernos de Saúde …, 2005 - SciELO Brasil
Brazil may have the highest absolute number of HTLV-I/II seropositive individuals in the
world. Screening potential blood donors for HTLV-I/II is mandatory in Brazil. The public …