Identifying children likely to benefit from antibiotics for acute sinusitis: a randomized clinical trial

N Shaikh, A Hoberman, TR Shope, JH Jeong… - JAMA, 2023 - jamanetwork.com
Importance The large overlap between symptoms of acute sinusitis and viral upper
respiratory tract infection suggests that certain subgroups of children being diagnosed with …

Treatment failure and adverse events after amoxicillin-clavulanate vs amoxicillin for pediatric acute sinusitis

TJ Savage, MP Kronman, SK Sreedhara, SB Lee… - JAMA, 2023 - jamanetwork.com
Importance Acute sinusitis is one of the most common indications for antibiotic prescribing in
children, with an estimated 4.9 million such prescriptions in the US annually. Consensus …

Next steps in ambulatory stewardship

HM Frost, AL Hersh, DY Hyun - Infectious Disease Clinics, 2023 - id.theclinics.com
Antibiotics are widely prescribed medications in the United States, with up to 95% of
antibiotic volumes prescribed in outpatient settings. 1 However, it is estimated that 30% to …

Factors associated with inappropriateness of antibiotic prescriptions for acutely ill children presenting to ambulatory care in high-income countries: a systematic review …

H Dillen, J Wouters, D Snijders… - Journal of …, 2024 - academic.oup.com
Background Acutely ill children are at risk of unwarranted antibiotic prescribing. Data on the
appropriateness of antibiotic prescriptions provide insights into potential tailored …

National disparities in antibiotic prescribing by race, ethnicity, age group, and sex in united states ambulatory care visits, 2009 to 2016

EH Young, KA Strey, GC Lee, TJ Carlson, JM Koeller… - Antibiotics, 2022 - mdpi.com
While efforts have been made in the United States (US) to optimize antimicrobial use, few
studies have explored antibiotic prescribing disparities that may drive future interventions …

Trends in Low-Value Care Among Children's Hospitals

SA House, JR Marin, ER Coon, SL Ralston, M Hall… - …, 2024 - publications.aap.org
Video Abstract BACKGROUND AND OBJECTIVES Longitudinal pediatric low-value care
(LVC) trends are not well established. We used the Pediatric Health Information System LVC …

Validation of a multi-analyte immunoassay for distinguishing bacterial vs. viral infections in a pediatric cohort

AK Chokkalla, E Tam, R Liang, AT Cruz, S Devaraj - Clinica Chimica Acta, 2023 - Elsevier
Background Clinical presentation of viral and bacterial infections or co-infections overlaps
significantly. Pathogen identification is the gold standard for appropriate treatment. Recently …

Assessment of prescribing practices and factors related to antibiotic prescribing in community pharmacies

SA Rabbani, SB Sridhar, M Safdar, PGM Rao… - Medicina, 2023 - mdpi.com
Background and Objectives: Overprescribing of antibiotics is one of the important
contributors of antimicrobial resistance globally. A high proportion of antibiotics prescribed in …

Comparative safety and attributable healthcare expenditures following inappropriate versus appropriate outpatient antibiotic prescriptions among adults with upper …

AM Butler, DS Brown, JG Newland… - Clinical Infectious …, 2023 - academic.oup.com
Background Little is known about the clinical and financial consequences of inappropriate
antibiotics. We aimed to estimate the comparative risk of adverse drug events and …

Utilization of broad‐versus narrow‐spectrum antibiotics for the treatment of outpatient community‐acquired pneumonia among adults in the United States

KB Nickel, MJ Durkin, MA Olsen… - … and drug safety, 2024 - Wiley Online Library
Purpose To characterize antibiotic utilization for outpatient community‐acquired pneumonia
(CAP) in the United States. Methods We conducted a cohort study among adults 18–64 …