Dronedarone, a noniodinated benzofuran derivative of amiodarone, is believed to have a
better side effect profile, and is currently undergoing phase III clinical trials. A novel method …

Sotalol has a weak fluorescence in aqueous solutions, so using a direct fluorescent method
is difficult. The competitive reaction between sotalol and palmatine for occupancy of the …

A simple, selective, and sensitive LC–MS/MS method was developed for the simultaneous
extraction and determination of eight beta-blockers (atenolol, sotalol, nadolol, pindolol …

Background: Exhaled breath condensate (EBC) could be used as a non-invasive and
alternative specimen to urine and blood for monitoring propranolol levels. A simple …

A liquid chromatographic tandem mass spectrometric method for the identification and
quantification of 18 cardiovascular drugs was developed in order to evaluate two cases of …

A detailed procedure for the analysis of four β‐blockers, acebutolol, labetalol, metoprolol
and propranolol, in human plasma by high‐performance liquid chromatography (LC) …

In total, three related substances (RS) associated with sotalol hydrochloride (STHCl) were
herein identified with a novel gradient high-performance liquid chromatography (HPLC) …

The interest in therapeutic drug monitoring has increased over the last few years. Inter‐and
intra‐patient variability in pharmacokinetics, plasma concentration related toxicity and …

β-blockers are a class of antihypertensive drugs that are used for the management of
cardiac arrhythmias, cardioprotection after myocardial infarction (heart attack) and …

Background: A highly sensitive, specific and rapid LC–ESI-MS/MS method has been
developed and validated for simultaneous quantification of amlodipine (AMD) and atenolol …