Analysis of carvedilol enantiomers in human plasma using chiral stationary phase column and liquid chromatography with tandem mass spectrometry
JC Poggi, FG Da Silva, EB Coelho, MP Marques… - Chirality, 2012 - Wiley Online Library
Carvedilol is an antihypertensive drug available as a racemic mixture.(−)‐(S)‐carvedilol is
responsible for the nonselective β‐blocker activity but both enantiomers present similar …
responsible for the nonselective β‐blocker activity but both enantiomers present similar …
Fast and sensitive analysis of beta blockers by ultra‐high‐performance liquid chromatography coupled with ultra‐high‐resolution TOF mass spectrometry
J Tomková, P Ondra, E Kocianová… - Biomedical …, 2017 - Wiley Online Library
This paper presents a method for the determination of acebutolol, betaxolol, bisoprolol,
metoprolol, nebivolol and sotalol in human serum by liquid–liquid extraction and ultra‐high …
metoprolol, nebivolol and sotalol in human serum by liquid–liquid extraction and ultra‐high …
A Sensitive Liquid Chromatography-Mass Spectrometric Method for Determination of Bisoprolol in Rat Serum after Pre-Column Derivatization
HA Shaheen, SO Bahaffi… - Journal of …, 2023 - academic.oup.com
Two derivatization regents were reacted with bisoprolol (BIS), followed by liquid-
chromatography-mass spectrometric analysis. 3-Bromomethyl-propyphenazone (BMP) and …
chromatography-mass spectrometric analysis. 3-Bromomethyl-propyphenazone (BMP) and …
Absorption barriers in the rat intestinal mucosa: 1. Application of an in situ perfusion model to simultaneously assess drug permeation and metabolism
DR Mudra, RT Borchardt - Journal of Pharmaceutical Sciences, 2010 - Elsevier
Modulation of intestinal drug absorption barriers can have a profound impact on the
bioavailability of orally administered compounds. With its commonality of use as an …
bioavailability of orally administered compounds. With its commonality of use as an …
Development of a validated spectrofluorimetric method for assay of sotalol hydrochloride in tablets and human plasma: application for stability-indicating studies
FA Ibrahim, AM El-Brashy, MI El-Awady… - Open …, 2019 - degruyter.com
The native fluorescence of sotalol hydrochloride (SOT) was used as a basis for establishing
a new method of analysis for SOT in tablets and spiked human plasma. The fluorescence of …
a new method of analysis for SOT in tablets and spiked human plasma. The fluorescence of …
[PDF][PDF] Visible spectrophotometric method for estimation of bisoprolol from its bulk and tablet formulation
ST Kumbhar, PP Shinde, DB Shinde… - Asian J Pharm Clin …, 2013 - academia.edu
The proposed method is new, simple, sensitive, reproducible, economical, accurate and
precise and can be successfully applied in estimation of bisoprolol. This method can find …
precise and can be successfully applied in estimation of bisoprolol. This method can find …
Development and validation of a liquid chromatography–mass spectrometry method for simultaneous determination of metoprolol and telmisartan in rat plasma and its …
A simple, rapid and sensitive high-performance liquid chromatography–tandem mass
spectrometry method has been developed and validated according to the Food and Drug …
spectrometry method has been developed and validated according to the Food and Drug …
Detection of acute overdose states by some antihypertensive drugs using gas chromatography-mass spectrometry
ES Melnikov, MV Belova, GV Ramenskaya - Journal of Analytical …, 2014 - Springer
Abstracts A method is developed for the detection of some antihypertensive drugs, atenolol,
bisoprolol, enalapril, metoprolol, nifedipine and propranolol by gas chromatography coupled …
bisoprolol, enalapril, metoprolol, nifedipine and propranolol by gas chromatography coupled …
Liquid chromatography tandem mass spectrometry method for determination of bisoprolol in human plasma using d5‐bisoprolol as the internal standard
G Liu, W Wang, J Jia, C Lu, Y Liu… - Biomedical …, 2010 - Wiley Online Library
A simple, reliable and sensitive liquid chromatography tandem mass spectrometry (LC‐
MS/MS) protocol was developed and validated for quantification of bisoprolol in human …
MS/MS) protocol was developed and validated for quantification of bisoprolol in human …