高效液相色谱-荧光法测定大鼠血浆中富马酸比索洛尔的浓度及药物动力学
谷福根， 郝朵 - 中南药学, 2014 - cqvip.com
目的建立大鼠血浆中富马酸比索洛尔(BF) 浓度的测定方法, 并研究大鼠灌胃给予BF
后的体内药动学. 方法以酒石酸美托洛尔为内标, 采用HPLC-荧光法, 测定大鼠血浆中药物浓度 …
后的体内药动学. 方法以酒石酸美托洛尔为内标, 采用HPLC-荧光法, 测定大鼠血浆中药物浓度 …
HPLC-MS/MS 法测定恒河猴血浆中地尔硫卓的质量浓度
付晓菲， 赵文军， 高锦 - 沈阳药科大学学报, 2014 - cqvip.com
目的建立恒河猴血浆中地尔硫卓质量浓度的HPLC-MS/MS 测定方法. 方法采用Agilent Zorbax
SB-C18 色谱柱(2.1 mm× 100 mm, 3.5 μm), 以乙腈-10 mmol· L^-1 醋酸铵(体积比75∶ 25) …
SB-C18 色谱柱(2.1 mm× 100 mm, 3.5 μm), 以乙腈-10 mmol· L^-1 醋酸铵(体积比75∶ 25) …
Development and validation of RP-HPLC-DAD method for determination of nine drugs and their eleven metabolites in plasma and urine: Plasma samples …
I Baranowska, A Wilczek, K Michał… - Journal of Liquid …, 2013 - Taylor & Francis
A new RP-HPLC-DAD method for determination of nine drugs and eleven metabolites in
body fluids was developed. The separation of drugs and metabolites (PAR, SOT, MET, ASP …
body fluids was developed. The separation of drugs and metabolites (PAR, SOT, MET, ASP …
Forced degradation studies and structural characterization of related substances of bisoprolol fumarate in finished drug product using LC–UV–MS/MS
EL Todevska, M Piponski, M Stefova - Journal of the Serbian …, 2022 - shd-pub.org.rs
Methods for determination of bisoprolol and related substances mostly use UV detection and
a phosphate buffer and are not suitable for MS detection. In this study, LC–UV–MS/MS for …
a phosphate buffer and are not suitable for MS detection. In this study, LC–UV–MS/MS for …
Challenges in therapeutic drug monitoring of digoxin and other antiarrhythmic drugs
A Dasgupta - Therapeutic Drug Monitoring, 2024 - Elsevier
Digoxin due to its narrow therapeutic range is a challenge for therapeutic drug monitoring
because digoxin immunoassays are affected by a variety of drugs and herbal supplements …
because digoxin immunoassays are affected by a variety of drugs and herbal supplements …
[PDF][PDF] Analysis of approaches to the development and validation of the methods of analysis of bisoprolol in drugs and biological liquids
LS Logoyda - Медична та клінічна хімія, 2019 - irbis-nbuv.gov.ua
Conclusions. In light of the benefits discussed in this review, we can conclude that analysts
are constantly working on developing new methods of analysis of bisoprolol in drugs and …
are constantly working on developing new methods of analysis of bisoprolol in drugs and …
液相色谱-串联质谱法测定人血浆中卡维地洛的浓度
张梦琪， 周秀锦， 陆川， 陆晓佩， 刘罡一， 贾晶莹… - 中国新药与临床 …, 2011 - cqvip.com
目的建立测定血浆中卡维地洛的液相色谱-串联质谱(LC—MS/MS) 方法. 方法血浆样品中加入内
标氘3-卡维地洛, 直接沉淀法处理样品. 色谱柱为CAPCELL PACK C18Ⅲ (100.0 mm× 2.0 mm …
标氘3-卡维地洛, 直接沉淀法处理样品. 色谱柱为CAPCELL PACK C18Ⅲ (100.0 mm× 2.0 mm …
[PDF][PDF] Talanta Open
NN AL-Hashimi, YS Al-Degs, EMA Al Momany… - researchgate.net
ABSTRACT A sensitive and simple microextraction approach was developed and validated
to simultaneously determine three antiarrhythmic drugs, propranolol, diltiazem, and …
to simultaneously determine three antiarrhythmic drugs, propranolol, diltiazem, and …
[PDF][PDF] Optimisation, Validation and Application of an Extractive Spectrophotometric Method for the Determination of Bisoprolol Fumarate in Pharmaceutical …
S Ashour - RJ. Aleppo Univ - researchgate.net
A simple and accurate method is presented for the determination of bisoprolol fumarate (BF)
in pure form and pharmaceutical forms. The method is based on the reaction of the above …
in pure form and pharmaceutical forms. The method is based on the reaction of the above …
液相色谱-串联质谱法检测血液中的美西律
严慧， 向平， 卜俊， 沈敏 - 法医学杂志, 2007 - cqvip.com
目的建立测定血液中美西律(mexiletine) 的液相色谱-串联质谱联用法(LC—MS/MS).
方法采用简便的乙腈蛋白沉淀法对血液进行预处理, 应用Allure PFP Propyl 液相柱分离 …
方法采用简便的乙腈蛋白沉淀法对血液进行预处理, 应用Allure PFP Propyl 液相柱分离 …