Oral sequelae of head and neck radiotherapy

A Vissink, J Jansma, FKL Spijkervet… - Critical Reviews in …, 2003 - journals.sagepub.com
In addition to anti-tumor effects, ionizing radiation causes damage in normal tissues located
in the radiation portals. Oral complications of radiotherapy in the head and neck region are …

[HTML][HTML] Oral management strategies for radiotherapy of head and neck cancer

Y Kawashita, S Soutome, M Umeda, T Saito - Japanese Dental Science …, 2020 - Elsevier
Radiotherapy, often with concomitant chemotherapy, has a significant role in the
management of head and neck cancer, however, radiotherapy induces adverse events …

Human salivary gland stem cells functionally restore radiation damaged salivary glands

S Pringle, M Maimets, M van der Zwaag… - Stem …, 2016 - academic.oup.com
Adult stem cells are often touted as therapeutic agents in the regenerative medicine field,
however data detailing both the engraftment and functional capabilities of solid tissue …

[HTML][HTML] Rescue of salivary gland function after stem cell transplantation in irradiated glands

IMA Lombaert, JF Brunsting, PK Wierenga, H Faber… - PloS one, 2008 - journals.plos.org
Head and neck cancer is the fifth most common malignancy and accounts for 3% of all new
cancer cases each year. Despite relatively high survival rates, the quality of life of these …

An update of the etiology and management of xerostomia

SR Porter, C Scully, AM Hegarty - Oral Surgery, Oral Medicine, Oral …, 2004 - Elsevier
Salivary gland disease gives rise to salivary gland enlargement, pain, and prolonged
xerostomia (dry mouth). Xerostomia is the most common long-standing problem for the …

Oral complications of radiotherapy

JJ Sciubba, D Goldenberg - The lancet oncology, 2006 - thelancet.com
Radiotherapy-induced damage in the oral mucosa is the result of the deleterious effects of
radiation, not only on the oral mucosa itself but also on the adjacent salivary glands, bone …

Radiation-related damage to dentition

AM Kielbassa, W Hinkelbein, E Hellwig… - The lancet …, 2006 - thelancet.com
Because of typical tissue reactions to ionising radiation, radiotherapy in the head and neck
region usually results in complex oral complications affecting the salivary glands, oral …

Oral mucositis

JE Raber-Durlacher, S Elad, A Barasch - Oral oncology, 2010 - Elsevier
Mucosal damage is one of the most common adverse effects of radiotherapy and of cytotoxic
therapy for cancer. With prevalence between 10% and 100%, depending of the cytotoxic …

[HTML][HTML] European Head and Neck Society recommendations for head and neck cancer survivorship care

I Verdonck-de Leeuw, C Dawson, L Licitra, JG Eriksen… - Oral Oncology, 2022 - Elsevier
Survivors of head and neck cancer can experience long-term consequences of the cancer
and subsequent treatments even after the cancer has resolved. Increasingly clinicians are …

Mechanisms of inflammatory responses to radiation and normal tissues toxicity: clinical implications

M Najafi, E Motevaseli, A Shirazi, G Geraily… - … journal of radiation …, 2018 - Taylor & Francis
Purpose: Cancer treatment is one of the most challenging diseases in the present era.
Among a few modalities for cancer therapy, radiotherapy plays a pivotal role in more than …